The Dermal Nevus and Statistics

Winkelmann, R. K.; Rocha, G. L.

doi:10.1001/archderm.1962.01590090052013

Cited by 38 publications

(7 citation statements)

References 14 publications

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“…The patients' demographics for the neurofibromas, and IDN studied in this series are very similar to those published in previous large series 15,57 , 58 . Our prevalence of a variety of histologic changes in NF‐1, SN and IDN is similar to the previously published results for IDN (see Table 4).…”

Section: Discussionsupporting

confidence: 87%

Melanocytic nevi are associated with neurofibromas in neurofibromatosis, type I, but not sporadic neurofibromas. A study of 226 cases*

Ball

Kho

2005

J Cutan Pathol

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Section: Discussionsupporting

confidence: 87%

Melanocytic nevi are associated with neurofibromas in neurofibromatosis, type I, but not sporadic neurofibromas. A study of 226 cases*

Ball

Kho

2005

J Cutan Pathol

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“…This frequency ranges from 0% (among 1,000 Caucasian peo ple in New York City examined by Pack et al [23] every one had at least one nevus) to 20% among 197 Scottish people [32]. In our Alemannic Caucasian population even in children of 10-14 years only 1.3% were found without any nevus.…”

Section: Discussionmentioning

confidence: 57%

Frequency of Acquired Melanonevocytic Nevi and Their Relationship to Skin Complexion in 939 Schoolchildren

Sigg

Pelloni²

1989

Dermatology

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In 939 schoolchildren aged 8–16 years skin complexion was determined by a system of seven categories. Anamnestic data concerning tanning ability and history of sunburns, however, were not considered owing to their obvious unreliability in children. Mean nevus count was 17.97 was significantly higher in boys than in girls and increased with age. There was a clear relation of mean nevus number and skin complexion: in fair skin type nevi are most frequent decreasing in number by increasing of pigment content. Additionally, children with freckles have higher mean nevus count in every category of skin complexion. All literature data critically reviewed as dealing with mean mole count are not comparable in several respects. In different races however such studies may serve as a basis for subsequent investigations concerning the questions of probably increasing number of melanonevocytic nevi.

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“…The proportion of bulky nevi was higher in the second and still higher in the third decade, but showed little change thereafter. Winkelmann and Rocha, 33 in 1962, studied 1200 nevi from seven decades. They also found a predominance of junctional nevi in the first decade and a significantly lower proportion in the second decade.…”

Section: Age-related Changes In Melanocytic Nevimentioning

confidence: 99%

Nevogenesis-New Thoughts Regarding a Classical Problem

Krengel¹

2005

The American Journal of Dermatopathology

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The development of melanocytic nevi is a multifactorial and heterogeneous biologic process that involves prenatal and postnatal steps. As a consequence, there are two main perspectives to nevi: that of a hamartoma and that of a benign tumor. In this review, dermatopathological studies on congenital and acquired nevi, including studies on age-related and location-dependent changes, are analyzed. These studies have lead to different hypothetical concepts on the evolution of individual lesions. In the light of findings from experimental embryology and stem cell biology, we discuss the histogenesis of nevi with special reference to the temporospatial sequence of melanocyte-basement membrane interactions and hair follicle genesis. Regarding the mechanisms of postnatal nevus development, epidemiological studies demonstrate the importance of constitutional and environmental influences, especially ultraviolet light. Possible molecular pathways of solar nevogenesis involve ultraviolet-induced alterations of the cellular microenvironment (eg, changes in the expression of cytokines and melanocyte adhesion molecules). Recent results and future directions of clinical and experimental research are presented.

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The Dermal Nevus and Statistics

Cited by 38 publications

References 14 publications

Melanocytic nevi are associated with neurofibromas in neurofibromatosis, type I, but not sporadic neurofibromas. A study of 226 cases*

Melanocytic nevi are associated with neurofibromas in neurofibromatosis, type I, but not sporadic neurofibromas. A study of 226 cases*

Frequency of Acquired Melanonevocytic Nevi and Their Relationship to Skin Complexion in 939 Schoolchildren

Nevogenesis-New Thoughts Regarding a Classical Problem

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