The Danish National Schizophrenia project. Outcome and treatment modalities

Abstract

AimsTo describe the rationale, design and methods of the Danish national Schoizophrenia Project, and to characterise the sample at inclusion and after 1 and 2 ys.MethodProspective, comparative,longitudinal multicenter-study (16 centers distributed all over Denmark), including 562 patients with a first episode psychosis, ICD 10 F- 2, sduccessively referred during two years.Patients were treated with three different intervention types1. supportive psychodynamic as a supplement to treatmen as usual, including antipsychotics (TAU), 2. assertive, integrated treatment with psychosocial and psychoeducation and antipsychotics 3. Treatment as usual. Data included psychopathology, social fundtion and sociodemographic data, at baseline, years 1 and 2.ResultComparing the three interventions showed a significantly better outcome for the interventions 1 and 2 than 3, TAU.