The correlation between motor impairments and event-related desynchronization during motor imagery in ALS patients

Abstract

BackgroundThe event-related desynchronization (ERD) in EEG is known to appear during motor imagery, and is thought to reflect cortical processing for motor preparation. The aim of this study is to examine the modulation of ERD with motor impairment in ALS patients. ERD during hand motor imagery was obtained from 8 ALS patients with a variety of motor impairments. ERD was also obtained from age-matched 11 healthy control subjects with the same motor task. The magnitude and frequency of ERD were compared between groups for characterization of ALS specific changes.ResultsThe ERD of ALS patients were significantly smaller than those of control subjects. Bulbar function and ERD were negatively correlated in ALS patients. Motor function of the upper extremities did was uncorrelated with ERD.ConclusionsALS patients with worsened bulbar scales may show smaller ERD. Motor function of the upper extremities did was uncorrelated with ERD.

Real and imaginary motion classification based on rough set analysis of EEG signals for multimedia applications

“…Thus, a particular pattern can be determined and removed from each recording. Similar results are achieved by the Independent Component Analysis (ICA) method [20,21,27,45].…”

“…It was determined that main phenomenon is alpha wave power decrease in a motor cortex in a hemisphere contra-lateral to the movement side [25,26,33], usually registered by C3 and C4 channels [38,41,51]. It is related to phenomena of event-related de-synchronization (ERD) [21,30,53]. Motion intent can be also classified by linear discriminant analysis (LDA) [21,25,26,31].…”

“…It is related to phenomena of event-related de-synchronization (ERD) [21,30,53]. Motion intent can be also classified by linear discriminant analysis (LDA) [21,25,26,31]. A recent presented application of k-means clustering and Principal Component Analysis (PCA) for steering of a simple robot [28] with a mental binary trigger, tested on 6 users.…”

“…Thus a frequency filtration cannot be applied, hence other approaches were developed to solve the problem. The common procedure is Signal-Space Projection (SSP) [21,43,46], involving spatial decomposition of the EEG signals for determining samples contaminated by the artefact. This method is based on the fact that the artefact signal repeatedly originates from the same location, e.g.…”

Altered cortical beta‐band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis

“…Additional analysis variables pertinent to neural signal interpretation include the selection of baseline period and frequency band of interest. Furthermore patient groups may differ in the degree to which they actively participate in a task, and this severely limits the conclusions that can be drawn from tasks of motor imagery (Kasahara et al, 2012; Lulé et al, 2007; Stanton et al, 2007a, 2007b). Riluzole administration could possibly dilute the reported ALS group effects, although analysis of the five remaining patients revealed a directionally similar trend.…”