The correlation between demographic factors and upper urinary tract stone composition in the Thai population

Arunkajohnsak, Noppon; Taweemonkongsap, Tawatchai; Leewansangtong, Sunai; Srinualnad, Sittiporn; Jongjitaree, Kantima; Chotikawanich, Ekkarin

doi:10.1016/j.heliyon.2020.e04649

Cited by 4 publications

(7 citation statements)

References 22 publications

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“…The beginning of urolithiasis prevalence studies in Thailand dates to 1961, with a reported prevalence of 17.7/100,000, which increased to 183.8/100,000 in the year 2005;[ 7 - 9 ] this had a significant impact on health systems due to the cost of diagnosis and treatment, as well as the loss of working hours due to the disease. [ 10 ] This led to the development of community treatment programs, resulting in a decreased prevalence of 90.75/100,000 people in 2018.…”

Section: Discussionmentioning

confidence: 99%

The changing composition of urinary calculi in Southern Thailand over the past 14 years

et al. 2022

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Objective: A worldwide increased incidence of urolithiasis has been observed over the past few decades. Insight into the composition of these stones can lead to enhanced medical treatment and outcomes. The objective of this study was to examine the distribution and chemical composition of urinary calculi in Southern Thailand over the past decade. Materials and Methods: An analysis was conducted on 2611 urinary calculi submitted to the Stone Analysis Laboratory, Songklanagarind Hospital, a single stone analysis laboratory in Southern Thailand. The analysis was performed from 2007 to 2020 using Fourier-transform infrared spectroscopy. The demographic results were described using descriptive statistical analyses, and the Chi-square test for trends was performed to identify changes in urinary calculi composition. Results: The patients’ demographic data revealed a male-to-female ratio of 2.2:1; the most common age group of affected men was 50–69 years, whereas the most common age group of affected women was 40–59 years. The most common components found in the calculi were uric acid (30.6%), mixed calcium oxalate with calcium phosphate (29.2%), and calcium oxalate (26.7%). We noted a trend of increasing uric acid calculi for 14 years (P = 0.00493), whereas the trend for the other major components was decreasing. Conclusion: The most common component of urinary calculi analyzed in Southern Thailand was uric acid, with a significant rising trend in proportion in the past decade; the trend of other major components, such as mixed calcium oxalate-calcium phosphate and calcium oxalate, decreased.

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Section: Discussionmentioning

confidence: 99%

The changing composition of urinary calculi in Southern Thailand over the past 14 years

et al. 2022

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“…1 Bladder stones are usually symptomatic; but in a few cases, they can also be asymptomatic. 2,3 Open cystolithotomy and endoscopic modalities are the available methods for the removal of bladder stones. 4 Open cystolithotomy is associated with more postoperative pain, prolonged hospital stays and wound scar as compared to endoscopic procedures.…”

Section: Introductionmentioning

confidence: 99%

An institutional review of endoscopic and open technique in the management of vesical calculus: a retrospective study

Karkee

Chaudhary²,

Kafle³

et al. 2022

Int Surg J

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Background: Vesical calculus means urolith in bladder. Cystolithotomy is the traditional treatment, but a percutaneous approach has been advocated. The objective was to compare open cystolithotomy with perurethral cystolithotripsy and suprapubic percutaneous cystolithotripsyused in the treatment of bladder stones.Methods: A retrospective study was conducted among 100 patients of bladder stone treated at a tertiary centre in Eastern Nepal from January 2014 to December 2019 who underwent open cystolithotomy and endoscopic procedures (perurethral cystolithotripsy and suprapubic percutaneous cystolithotripsy). Data were analysed using SPSS version 11.5 at p value less than 0.05 taken as significant.Results: Statistical significant difference was observed in operating time, duration of catheterization and duration of hospital stay in both open and endoscopic management of vesical calculus (p value=0.0001). General complications were observed in 90% cases of open cystolithotomy and 33.9% cases of endoscopic procedure respectively.Conclusions: Endoscopic procedure is safe and efficacious method of urinary bladder stone removal with low incidence of complications.

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“…Urolithiasis is a frequently occurring urological disease characterized by the presence of a stone anywhere along the urinary tract, with a high recurrence rate [1]. Arunkajohnsak et al found that the major components of the stone consist of calcium oxalate (60%), calcium phosphate (26%), uric acid (8.3%), magnesium ammonium phosphate (4.0%), cystine (1.0%), and ammonium hydrogen urate (0.6%) [2]. The pathogenesis is a complex biochemical process that is not completely understood.…”

Section: Introductionmentioning

confidence: 99%

Increased Sulfation in Gracilaria fisheri Sulfated Galactans Enhances Antioxidant and Antiurolithiatic Activities and Protects HK-2 Cell Death Induced by Sodium Oxalate

et al. 2022

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Urolithiasis is a common urological disease characterized by the presence of a stone anywhere along the urinary tract. The major component of such stones is calcium oxalate, and reactive oxygen species act as an essential mediator of calcium oxalate crystallization. Previous studies have demonstrated the antioxidant and antiurolithiatic activities of sulfated polysaccharides. In this study, native sulfated galactans (N-SGs) with a molecular weight of 217.4 kDa from Gracilaria fisheri were modified to obtain lower molecular weight SG (L-SG) and also subjected to sulfation SG (S-SG). The in vitro antioxidant and antiurolithiatic activities of the modified substances and their ability to protect against sodium oxalate-induced renal tubular (HK-2) cell death were investigated. The results revealed that S-SG showed more pronounced antioxidant activities (DPPH and O2− scavenging activities) than those of other compounds. S-SG exhibited the highest antiurolithiatic activity in terms of nucleation and aggregation, as well as crystal morphology and size. Moreover, S-SG showed improved cell survival and increased anti-apoptotic BCL-2 protein in HK-2 cells treated with sodium oxalate. Our findings highlight the potential application of S-SG in the functional food and pharmaceutical industries.

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The correlation between demographic factors and upper urinary tract stone composition in the Thai population

Cited by 4 publications

References 22 publications

The changing composition of urinary calculi in Southern Thailand over the past 14 years

The changing composition of urinary calculi in Southern Thailand over the past 14 years

An institutional review of endoscopic and open technique in the management of vesical calculus: a retrospective study

Increased Sulfation in Gracilaria fisheri Sulfated Galactans Enhances Antioxidant and Antiurolithiatic Activities and Protects HK-2 Cell Death Induced by Sodium Oxalate

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