2016
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Abstract: Recent modeled estimates suggest that blood transfusions account for a very low proportion of new HIV infections in SSA, likely an order of magnitude lower than 5% to 10%. Direct quantification of risk is challenging given the paucity of data on the variables that impact transfusion-associated HIV. Specifically, data on HIV incidence in blood donors, blood bank laboratory test performance, and posttransfusion surveillance are lacking. Findings suggest an urgent need for improved surveillance and modeling of tr… Show more

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“…Despite uncertainty in the exact rates of transmission, blood transfusion is still considered to be a contributing mode of viral transmission in parts of Africa. Proportion of new HIV infections might ranges from 5 to 10% [ 5 ]. Similarly, 12.5% of patients at risk of post transfusion hepatitis [ 6 ].…”
Section: Introductionmentioning
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“…Despite uncertainty in the exact rates of transmission, blood transfusion is still considered to be a contributing mode of viral transmission in parts of Africa. Proportion of new HIV infections might ranges from 5 to 10% [ 5 ]. Similarly, 12.5% of patients at risk of post transfusion hepatitis [ 6 ].…”
Section: Introductionmentioning
“…Historically, a statistic of 5% to 10% of new cases was cited, a claim for which a 2016 review found no primary support. 41 Instead, the findings suggested that only 1% of new HIV infections are attributable to transfusion-a figure complicated by a lack of published HIV prevalence data in blood donors and deficient posttransfusion surveillance. 41 Additionally, the rates of preseroconversion "window period infections" are not widely available yet, likely because new infections are given near exclusive reliance on antibody-based screening.…”
Section: Biological Testing and Pathogen Reduction Of Blood Productsmentioning
“…In some cases, outdated or unsubstantiated statistics have been used to support policy decisions. 41 The absence of accurate data weakens any economic foundation for policy change while transfusion recipients remain at unquantified risk. Region-specific research is needed, as was highlighted at a workshop in 2017 at the National Heart Lung and Blood Institute.…”
Section: 962mentioning
“…Nevertheless, the residual risks have almost certainly decreased substantially in the past two decades. The authors of a recent publication reviewing the United Nations Programme on HIV and AIDS (UNAIDS) modes of transmission reports, representing 15 countries, conclude that between 0 and 1Á1% of new HIV infections per year (median 0Á2% or approximately 2 out of 1000 new infections per year) may be attributable to blood transfusions [27]. Once again, while this is much lower than an 1988 estimate (albeit an estimate that was never data-based) of 5-10% of all new HIV infections, it remains at a level that would be unacceptable in HIC [28].…”
Section: Hiv Hepatitis B (Hbv) and Hepatitis C (Hcv)mentioning