1984
DOI: 10.1001/archderm.120.11.1441
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The clinical spectrum of the persistent light reactor

Abstract: Eight patients had a chronic photodermatitis of five to 19 years' duration. The clinical and photobiological features were consistent with the pattern observed in persistent light reactors. Severity and clinical presentation, however, were quite variable, ranging from a few isolated papules to extensive lichenification involving the entire exposed skin. Three had positive photopatch tests to halogenated salicylanilides, while the remaining five reacted to musk ambrette. Exposure of the uninvolved skin to UV-B … Show more

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Cited by 8 publications
(5 citation statements)
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“…The term persistent light reaction (PLR) was coined to describe a state of continued photosensitivity, manifest as a dermatitis after an initial episode of photocontact allergy, confirmed by positive photopatch tests, with subsequent ongoing photosensitivity even after withdrawal of the culprit topical photoallergen, typically halogenated salicylanilide or musk ambrette (54)(55)(56)(57)(58)(59)(60). The term was later encompassed within the spectrum of chronic actinic dermatitis and indeed, there is no convincing evidence in support of the PLR, with most cases retrospectively now being considered to fall within the spectrum of chronic actinic dermatitis (61,62).…”
Section: Persistent Light Reactionmentioning
confidence: 99%
“…The term persistent light reaction (PLR) was coined to describe a state of continued photosensitivity, manifest as a dermatitis after an initial episode of photocontact allergy, confirmed by positive photopatch tests, with subsequent ongoing photosensitivity even after withdrawal of the culprit topical photoallergen, typically halogenated salicylanilide or musk ambrette (54)(55)(56)(57)(58)(59)(60). The term was later encompassed within the spectrum of chronic actinic dermatitis and indeed, there is no convincing evidence in support of the PLR, with most cases retrospectively now being considered to fall within the spectrum of chronic actinic dermatitis (61,62).…”
Section: Persistent Light Reactionmentioning
confidence: 99%
“…They cited repeated application of salicylanilide soaps to most of the body as an explanation as to why many affected patients had generalized sensitivity. Cases labelled as PLR to halogenated salicylanilides and fragrances continued to be reported (22). However, the similarities of such patients with other photosensitive states led to the subsequent inclusion of PLR within, at that time, a newly defined unifying diagnosis of CAD (23, 24).…”
Section: The Persistent Light Reactor (Plr)mentioning
confidence: 99%
“…This patient, however, remained sensitive to sunlight for extended periods, even after withdrawal of this photoallergen from his environment. Therefore, he is believed to have had photoallergic contact dermatitis in SHORT COMMUNICATIONS addition to contact dermatitis, and can be considered to be a persistent light reactor (6), making this the first such case attributable to Daconil®.…”
Section: Discussionmentioning
confidence: 99%