The Clinical Significance of "Measurement Microcephaly"

The Predictive Value of Microcephaly During the First Year of Life for Mental Retardation at Seven Years

“…The results therefore do not apply to children who are microcephalic at birth but show catch-up head growth, or to children whose head circumference steadily falls from the mean without showing as great a deviation as 3 SD by the age of one year. Serial measurements showing the head circumference to be falling from the mean may be of great significance, regardless of the absolute size of the head, as has been suggested by Avery et al (1972).…”

Extreme Deprivation in Early Childhood–i. Diverse Outcomes for Three Siblings From an Extraordinary Family

“…A deviation of this degree is often taken as representing significant microcephaly (e.g. Martin, 1970;Avery et al, 1972), but the coincidence of the condition in mother and daughter is an extremely unusual one. Microcephaly may be genetically determined, but when it is, it is usually inherited as a recessive or sex-linked phenomenon (Warkany and St. J. Dignan, 1974).…”

A syndrome of microcephaly and retinal pigmentary abnormalities without mental retardation in a family with coincidental autosomal dominant hyperreflexia

“…A number of authors have commented on the phenomenon of normal intelligence in severely microcephalic children and have advised caution in presuming severe retardation in all infants with microcephaly [Avery et al, 1971;Martin, 19701. Such caution should be extended to microcephalic children with retinal abnormalities.…”