The clinical effectiveness and cost-effectiveness of point-of-care tests (CoaguChek system, INRatio2 PT/INR monitor and ProTime Microcoagulation system) for the self-monitoring of the coagulation status of people receiving long-term vitamin K antagonist therapy, compared with standard UK practice: systematic review and economic evaluation

Abstract

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Clinical Outcomes in 3343 Children and Adults With Rheumatic Heart Disease From 14 Low- and Middle-Income Countries

“…While self-monitoring using point-of-care devices may be theoretically appealing, they are currently not affordable for the majority of patients in Africa and Asia. 26,27 Moreover it is unknown if patients in LMICs can effectively self-monitor and adjust their VKA doses. Perhaps novel approaches need to be tested, such as the recruitment of educated and motivated individuals from the community (e.g., local school teachers), and may be useful surrogate healthcare providers to perform home monitoring.…”

Predictors of anticoagulation quality in 15 834 patients performing patient self‐management of oral anticoagulation with vitamin K antagonists in real‐life practice: a survey of the International Self‐Monitoring Association of Orally Anticoagulated Patients

“…However, the overall quality of anticoagulation with VKA is still variable (Dlott et al, 2014) and only a minority of patients are trained for PSM (Ferguson et al, 2016). Efficacy and safety in comparison to standard care was established in a number of randomized clinical trials, and data were pooled in several meta-analyses (Garcia- Alamino et al, 2010;Bloomfield et al, 2011;Heneghan et al, 2012;Sharma et al, 2015). In contrast, patient self-testing (PST) only enables patients to determine INR values, with dose-adjustments being made by medical professionals.…”

Efficacy of Point-of-Care Testing (POCT) in Reducing Total Waiting Time at Warfarin Clinic of a District Hospital: A Cohort Study

“…• Self-management: point-of-care test carried out by trained patient, followed by interpretation of test result and adjustment of dosage of anticoagulant according to a predefined protocol [10]. The point-of-care testing coagulometer measures the prothrombin time and INR (the globally recommended unit for measuring thromboplastin time) in people on oral anticoagulation (vitamin K antagonist) therapy [10].…”

“…The point-of-care testing coagulometer measures the prothrombin time and INR (the globally recommended unit for measuring thromboplastin time) in people on oral anticoagulation (vitamin K antagonist) therapy [10]. The POC devices use electrochemical methods or function by drawing a precise amount of blood into a microchannel and detect clot formation when the blood movement decreases below a predetermined rate [5].…”