The Clinical Course of Multiple Sclerosis During Pregnancy and the Puerperium

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

“…The characteristics of our population were similar to those of previous studies that have been reported in the literature [2,6,12,20]. The fact that the onset of MS was earlier in nulliparous patients might explain the absence of pregnancies in this population.…”

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

“…The characteristics of our population were similar to those of previous studies that have been reported in the literature [2,6,12,20]. The fact that the onset of MS was earlier in nulliparous patients might explain the absence of pregnancies in this population.…”

Th1/Th2 cytokine patterns and clinical profiles during and after pregnancy in women with multiple sclerosis

“…Indeed, only two patients out of eight experienced mild relapses postpartum. This finding is not in keeping with the recognized observations of increased rate of relapses [6][7][8][9][10] which is explainable by the fact that maintenance immunotherapy was resumed in a majority of the patients within 2 weeks of delivery. It should also be pointed out that patients were treated with IFNh 2 weeks after delivery, and this may be a confounding factor in terms of preventing the expected increase in rates of relapses in the first 6 months postpartum (5)(6)(7)(8)(9)(10).…”

Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy

“…Over a period of 3 months after delivery, relapse rate increased to a level higher than before pregnancy followed by a decrease to pre-pregnancy rate during the next 6 to 9 months. These results confirmed the findings of previous partly retrospective, partly quite small studies [45-47] and were verified by following surveys [48,49]. Relapses in the year before and during pregnancy are supposed to be a risk factor as they lead to a 1.7- to 1.8-fold increase of postpartum relapses [50], although these results could not be confirmed by another survey [51].…”

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

“…The characteristics of our population were similar to those of previous studies that have been reported in the literature [2,6,12,20]. The fact that the onset of MS was earlier in nulliparous patients might explain the absence of pregnancies in this population.…”

Th1/Th2 cytokine patterns and clinical profiles during and after pregnancy in women with multiple sclerosis

“…Indeed, only two patients out of eight experienced mild relapses postpartum. This finding is not in keeping with the recognized observations of increased rate of relapses [6][7][8][9][10] which is explainable by the fact that maintenance immunotherapy was resumed in a majority of the patients within 2 weeks of delivery. It should also be pointed out that patients were treated with IFNh 2 weeks after delivery, and this may be a confounding factor in terms of preventing the expected increase in rates of relapses in the first 6 months postpartum (5)(6)(7)(8)(9)(10).…”

Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy

“…Over a period of 3 months after delivery, relapse rate increased to a level higher than before pregnancy followed by a decrease to pre-pregnancy rate during the next 6 to 9 months. These results confirmed the findings of previous partly retrospective, partly quite small studies [45-47] and were verified by following surveys [48,49]. Relapses in the year before and during pregnancy are supposed to be a risk factor as they lead to a 1.7- to 1.8-fold increase of postpartum relapses [50], although these results could not be confirmed by another survey [51].…”

Effects of pregnancy and child birth on urinary symptoms and urodynamics in women with multiple sclerosis

“…The characteristics of our population were similar to those of previous studies that have been reported in the literature [2,6,12,20]. The fact that the onset of MS was earlier in nulliparous patients might explain the absence of pregnancies in this population.…”

Th1/Th2 cytokine patterns and clinical profiles during and after pregnancy in women with multiple sclerosis

“…Indeed, only two patients out of eight experienced mild relapses postpartum. This finding is not in keeping with the recognized observations of increased rate of relapses [6][7][8][9][10] which is explainable by the fact that maintenance immunotherapy was resumed in a majority of the patients within 2 weeks of delivery. It should also be pointed out that patients were treated with IFNh 2 weeks after delivery, and this may be a confounding factor in terms of preventing the expected increase in rates of relapses in the first 6 months postpartum (5)(6)(7)(8)(9)(10).…”

Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy

“…Over a period of 3 months after delivery, relapse rate increased to a level higher than before pregnancy followed by a decrease to pre-pregnancy rate during the next 6 to 9 months. These results confirmed the findings of previous partly retrospective, partly quite small studies [45-47] and were verified by following surveys [48,49]. Relapses in the year before and during pregnancy are supposed to be a risk factor as they lead to a 1.7- to 1.8-fold increase of postpartum relapses [50], although these results could not be confirmed by another survey [51].…”