The chromosomes of the house mouse

Cox, Elizabeth K.

doi:10.1002/jmor.1050430103

Cited by 25 publications

(6 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The majority of univalents occurring in both of our strains belonged to the small chromosome groups. This is not surprising since small chromosomes have fewer chiasmata (S l iz y n s k i, 1960) and have been observed to separate precociously (Cox, 1926). E d w a r d s (1970) found widely separated univalents belonging to the 21-22 group in an oocyte taken from a 35-year-old woman.…”

Section: Discussionmentioning

confidence: 99%

Chiasma and univalent frequencies in aging female mice

Luthardt¹,

Palmer²,

Yu³

1973

Cytogenet Genome Res

View full text Add to dashboard Cite

Oocytes were obtained from C57BL/6J and ICR female mice ranging in age from six weeks to 15 months. Both strains demonstrated a significant increase in univalents and a significant decrease in chiasma frequencies at metaphase I with age. Strain differences were observed with respect to the specific type of univalent formation and the regression of chiasma frequency on age. Univalent formation was nonrandom and involved small chromosomes predominantly. Although the percentage of oocytes possessing univalents increased significantly with age, the vast majority possessed only one pair of univalents.

show abstract

Section: Discussionmentioning

confidence: 99%

Chiasma and univalent frequencies in aging female mice

Luthardt¹,

Palmer²,

Yu³

1973

Cytogenet Genome Res

View full text Add to dashboard Cite

show abstract

“…Until 1969, geneticists and cytogeneticists believed that the karyotype of virtually all house mice (Mus musculus or Mus domesticus) consisted of 40 acrocentric chromosomes (Cox, 1926). Although animals with fewer than 40 chromosomes had now and then been found among laboratory mice (Evans, Lyon & Daglish, 1964;Leonard & DeKnudt, 1967;White & Tijo, 1967;Baranov & Dyban, 1971), they were regarded as rare exceptions.…”

Section: Introductionmentioning

confidence: 99%

Genetic variation of wild mouse populations in southern Germany: I. Cytogenetic study

Adolph

Klein

1983

Genet. Res.

View full text Add to dashboard Cite

Some 400 wild mice (Mus domesticus) from southern Germany (the triangle formed by the cities Tubingen, Heidenheim and Friedrichshafen) were karyotyped and, in 243 of them, the chromosome compositions were determined by banding techniques. Virtually all mice tested carried at least one pair of metacentric chromosomes; some mice had up to ten metacentric chromosomes. Based on their chromosome composition, five mouse populations could be distinguished. Population I was characterized by the diploid chromosome number of In = 38 and the presence of two copies of metacentric chromosome Rb(4.12)lTu. This translocation was also found in virtually all mice captured in southern Germany, almost always in a homozygous state. Mice of other populations had extra metacentric chromosomes Rb(5 .15)15Tu (population II), Rb(13.14)17Tu (population III), Rb(5.14)18Tu (population IV) and Rb(11.13)6Tu (population V). In addition, rare variants (1 or 2 mice) were found in the different populations, which were heterozygous for additional metacentric chromosomes. Population V was quite heterogeneous in that it contained up to five metacentric chromosomes in addition to those mentioned. The number and the composition of these metacentric chromosomes varied from place to place. With the exception of population I, the individual populations occupied geographically distinct areas: Representatives of population I were found concentrated in one area, but, in addition, some were scattered over the entire studied region.

show abstract

“…The crucial studies of the second division have been carried out in insects and in various forms of plants. There are only a few workers such as WINIWARTER (1912,1919), WINIWARTER and OGUMA (1926), Cox (1926) Except NAKAMURA and MINOUCHI, however, none of these authors have shown the diad nature of the chromosomes in the metaphase of the second division. Generally the chromosomes in the metaphase of the second division resemble those of the anaphase of the first division in shape and structure, and those in the anaphase of the second those of the spermatogonium.…”

Section: Discussionmentioning

confidence: 99%