Abstract:AbstractRegeneration of arterial endothelium after injury is critical for the maintenance of normal blood flow, cell trafficking, and vascular function. Using mouse models of carotid injury, we show that the transition from a static to a dynamic phase of endothelial regeneration is marked by a strong increase in endothelial proliferation, which is accompanied by induction of the chemokine CX
CL1 in endothelial cells near the wound edge, leading to progressive recruitment of Ly6Clo monocytes expressing high l…
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