The Case for Rhodobacter Sphaeroides as a probiotic: Applications for Human Health and Ulcerative Colitis

Abstract

In this short review, the mechanisms through which the probiotic administration of non-pathogenic bacterium Rhodobacter Sphaeroides could contribute to human health in general, and more specifically, the treatment of ulcerative colitis, are explored. This review is built around the concept that the mitochondrion is the key player in the pathogenesis of ulcerative colitis, and proposes ways that the probiotic could contribute to a more optimal environment for mitochondrial functioning, namely through reduction of inflammation and production of beneficial compounds like ubiquinone and bacteria-derived carotenoids. It concludes with the current state of the research involving Rhodobacter Sphaeroides as a probiotic and suggests possible future directions.