The Burden of Premature Mortality in Turkey in 2001 and 2008

Tokuç, Burcu; Ayhan, Serap; Saraçoğlu, Gamze Varol

doi:10.5152/balkanmedj.2016.151277

Cited by 4 publications

(5 citation statements)

References 12 publications

(23 reference statements)

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“…Our finding of diabetes, hypertension and smoking being the independent risk factors of premature mortality, largely support previous findings [3]. Although some previous studies, using case-control or cross-sectional design, conducted among Middle-East populations [13, 14], have investigated the impact of different risk factors and mortality events, to the best of our knowledge, none have been conducted using a population-based cohort study design.…”

Section: Discussionsupporting

confidence: 90%

Incidence and associated risk factors for premature death in the Tehran Lipid and Glucose Study cohort, Iran

et al. 2019

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Background The incidence and associated risk factors for premature death were investigated in a population-based cohort study in Iran. Methods A total of 7245 participants (3216 men), aged 30–70 years, were included. We conducted Cox proportional hazards models to identify the risk factors for premature death. For each risk factor, hazard ratio (HR), 95% confidence intervals (95% CI) and population attributable fraction (PAF) were calculated. Results After a median follow-up of 13.8 years, 262 premature deaths (153 in men) occurred. Underlying causes of premature deaths were cardiovascular disease (CVD) ( n = 126), cancer ( n = 51), road injuries ( n = 15), sepsis and pneumonia ( n = 9) and miscellaneous reasons ( n = 61). The age-standardized incident rate of premature death was 2.35 per 1000 person years based on WHO standard population. Hypertension [HR 1.40, 95% CI (1.07–1.83)], diabetes (2.53, 1.94–3.29) and current smoking (1.58, 1.16–2.17) were significant risk factors for premature mortality; corresponding PAFs were 12.3, 22.4 and 9.2%, respectively. Overweight (body mass index (BMI): 25–29.9 kg/m 2 ) (0.65, 0.49–0.87) and obesity (BMI ≥30 kg/m 2 ) (0.67, 0.48–0.94) were associated with decreased premature mortality. After replacing general adiposity with central adiposity, we found no significant risk for the latter (0.92, 0.71–1.18). Moreover, when we excluded current smokers, those with prevalent cancer/cardiovascular disease and those with survival of less than 3 years, the inverse association between overweight (0.59, 0.39–0.88) and obesity (0.67, 0.43–1.04), generally remained unchanged; although, diabetes still showed a significant risk (2.62, 1.84–3.72). Conclusions Controlling three modifiable risk factors including diabetes, hypertension and smoking might potentially reduce mortality events by over 40%, and among these, prevention of diabetes should be prioritized to decrease burden of events. We didn’t confirm a negative impact of overweight and obesity status on premature mortality events.

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Section: Discussionsupporting

confidence: 90%

Incidence and associated risk factors for premature death in the Tehran Lipid and Glucose Study cohort, Iran

et al. 2019

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“…The first method is the use of an aspirational life table, such as used in the GBD study, which is referred to as the ideal standard [ 3 ]. Many other national studies, such as those in Australia, New Zealand and Turkey [ 32 – 34 ] have adopted this approach. A second approach is to use observed, or national life tables, which can be calculated from source data and are representative of the populations for which estimates are being reported.…”

Section: Estimation Of Yllsmentioning

confidence: 99%

Reflections on key methodological decisions in national burden of disease assessments

et al. 2020

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Background Summary measures of population health are increasingly used in different public health reporting systems for setting priorities for health care and social service delivery and planning. Disability-adjusted life years (DALYs) are one of the most commonly used health gap summary measures in the field of public health and have become the key metric for quantifying burden of disease (BoD). BoD methodology is, however, complex and highly data demanding, requiring a substantial capacity to apply, which has led to major disparities across researchers and nations in their resources to perform themselves BoD studies and interpret the soundness of available estimates produced by the Global Burden of Disease Study. Methods BoD researchers from the COST Action European Burden of Disease network reflect on the most important methodological choices to be made when estimating DALYs. The paper provides an overview of eleven methodological decisions and challenges drawing on the experiences of countries working with BoD methodology in their own national studies. Each of these steps are briefly described and, where appropriate, some examples are provided from different BoD studies across the world. Results In this review article we have identified some of the key methodological choices and challenges that are important to understand when calculating BoD metrics. We have provided examples from different BoD studies that have developed their own strategies in data usage and implementation of statistical methods in the production of BoD estimates. Conclusions With the increase in national BoD studies developing their own strategies in data usage and implementation of statistical methods in the production of BoD estimates, there is a pressing need for equitable capacity building on the one hand, and harmonization of methods on the other hand. In response to these issues, several BoD networks have emerged in the European region that bring together expertise across different domains and professional backgrounds. An intensive exchange in the experience of the researchers in the different countries will enable the understanding of the methods and the interpretation of the results from the local authorities who can effectively integrate the BoD estimates in public health policies, intervention and prevention programs.

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“…In our study, YLL due to Conditions originating in the perinatal period, decreased. The expansion of prenatal diagnosis and prenatal care, the increase in giving birth in health facilities and the expansion of neonatal intensive care in the country have contributed to the improved survival of newborns and children in this period ( 2 ).…”

Section: Discussionmentioning

confidence: 99%

“…Traditionally, mortality rates are used to estimate public health problems and determine the relative significance of different causes of mortality, but they cannot necessarily determine the burden of premature death, which is an important indicator of the health status of a population ( 1 ). The classical rates of mortality are affected by diseases that are common in older age groups, so they may not fully exhibit the burden of premature mortality ( 2 ). Premature death is an important indicator and premature mortality reduction is considered as one of the goals of sustainable development by the WHO ( 3 ) .…”

Section: Introductionmentioning

confidence: 99%

The Burden of Premature Mortality in Southern Iran during 2004-2019 Using Standard Expected Years of Life Lost: A Population-Based Study

Mirahmadizadeh,

Hassanzadeh,

Janfada

et al. 2023

ijph

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Background: Traditionally, mortality rates are used to estimate public health problems and determine the relative significance of different causes of mortality, but they cannot necessarily determine the burden of premature death. We aimed to investigate the 16-year trend of burden of premature mortality in Southern Iran. Methods: In this cross-sectional study, all deaths due to various causes of death in Fars Province from the electronic population-based death registration system (EDRS) were obtained. Crude and age-standardized mortality rate, Years of Life Lost (YLL) and YLL rate data were calculated and to examine the trend, joinpoint regression was used. Results: During the study period, 281,903 deaths occurred, of which, 59.85% (n=168,735) occurred in men. Also, 42.18% of these deaths (n=118,610) occurred due to cardiovascular diseases (CVDs). The total number of YLLs due to premature death was 4,154,828 years. Of these, 2,591,564 years (62.37%) were in men. The highest number of YLL was due to CVDs, external causes of death and cancer. Trend of YLL rate due to premature mortality was decreasing: the annual percent change (APC) was -2.1% (95% CI -2.6 to -1.6, P<0.001) for males, -0.9% (95% CI -1.4 to -0.4, P=0.002) (P=0.002) for females. Conclusion: Although the trend of premature death has been decreasing during the years of study, but the seven major causes of premature death in 2004 to 2019 were non-communicable diseases, especially ischemic heart diseases, stroke, external cause of morbidity, and cancer. Furthermore, our findings indicate a change in the role of non-communicable diseases in premature mortality in recent years.

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The Burden of Premature Mortality in Turkey in 2001 and 2008

Cited by 4 publications

References 12 publications

Incidence and associated risk factors for premature death in the Tehran Lipid and Glucose Study cohort, Iran

Incidence and associated risk factors for premature death in the Tehran Lipid and Glucose Study cohort, Iran

Reflections on key methodological decisions in national burden of disease assessments

The Burden of Premature Mortality in Southern Iran during 2004-2019 Using Standard Expected Years of Life Lost: A Population-Based Study

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