The burden of disease due to tuberculosis in the state of Santa Catarina, Brazil

Abstract

OBJECTIVE:To estimate the burden of disease due to tuberculosis in the state of Santa Catarina, Brazil, in 2009.METHODS:This was an epidemiological study with an ecological design. Data on tuberculosis incidence and mortality were collected from specific Brazilian National Ministry of Health databases. The burden of disease due to tuberculosis was based on the calculation of disability-adjusted life years (DALYs). The DALYs were estimated by adding the years of life lost (YLLs) and years lived with disability (YLDs). Absolute values were transformed into rates per 100,000 population. The rates were calculated by gender, age group, and health care macroregion.RESULTS:The burden of disease due to tuberculosis was 5,644.27 DALYs (92.25 DALYs/100,000 population), YLLs and YLDs respectively accounting for 78.77% and 21.23% of that total. The highest rates were found in males in the 30-44 and 45-59 year age brackets, although that was not true in every health care macroregion. Overall, the highest estimated burden was in the Planalto Norte macroregion (179.56 DALYs/100,000 population), followed by the Nordeste macroregion (167.07 DALYs/100,000 population).CONCLUSIONS:In the majority of the health care macroregions of Santa Catarina, the burden of disease due to tuberculosis was concentrated in adult males, the level of that concentration varying among the various macroregions.

Spatial distribution of tuberculosis in a municipality in the interior of São Paulo, 2008-2013

“…It was observed the predominance of males, in people in economically active age range, with less than eight years of education. These findings are in acordance with other studies carried out in other Brazilian scenarios 8 - 9 . Similarly, the study is consistent with the literature regarding the predominant clinical form of the disease, in which pulmonary TB was the most prevalent 2 , 7 - 8 .…”

Burden of tuberculosis trends in a Brazilian southern state

“…As it was expected, the burden of tuberculosis in Santa Catarina was higher among men than among women, which agrees with previously published epidemiological studies 7,10,20 . Mexico experienced a 56% incidence of tuberculosis among men in 1990-2010 20 , whereas in the Brazilian state of Minas Gerais, the rate was even higher (60.6%) 9 .…”

“…YLL, YLD, and DALY rates/100,000 inhabitants according to gender in Santa Catarina, Brazil, 2007. Rates 10 . The findings of our study are, for the most part, lower to those reported by other authors.…”

“…In addition to the studies developed by the Brazilian National School of Public Health for Brazil 8 and for the state of Minas Gerais 9 , no other studies with the same methodology were found, particularly regarding tuberculosis. An exception to this is the study by Ferrer et al 10 , which has estimated the burden of tuberculosis in the state of Santa Catarina in 2009. However, there are no studies assessing temporal trends at national or regional level.…”

Tendência da mortalidade por tuberculose no estado do Paraná, Brasil – 1998 a 2012

“…It accounts for a quarter of preventable deaths in developing countries, with emphasis on adults generally and men aged 45-59 years old 1,2 . It is known as the "neglected calamity" not yet resolved in this century 3 .…”