The biological properties of carbon nanofibers decorated with β-tricalcium phosphate nanoparticles

Liu, Haiyang; Cai, Qing; Lian, Pengfei; Zhou, Fang; Duan, Shun; Ryu, Seung‐Kon; Yang, Xiaoping; Deng, Xuliang

doi:10.1016/j.carbon.2010.02.042

Cited by 27 publications

(31 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The structural integrity of CNFs was usually deteriorated by covalently/noncovalently decorated inorganic nanoparticles. [13][14][15][16] In comparison with cases of introducing M or MO x nanoparticles into electrospinning PAN solution directly, the electrospinning/sol-gel technique produced CNF/M or CNF/MO x composites conquered the disadvantage of serious aggregation of nanoparticles in the solution and in resulting nanobers. [8][9][10][11] The process showed advantages of catalyst-free preparation and strong exibility in tailoring the strength and elastic modulus of CNFs by regulating the carbonization temperatures and alignment degrees.…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Polyacrylonitrile (PAN)-based CNFs produced from solution electrospinning, pre-oxidation and carbonization have provided a feasible way to modify CNFs and improve the performances of currently available CNFs. [13][14][15][16] Materials including CNF/b-TCP, 13 22,23 had been intensively studied as photocatalyst, Liion battery anode, energy storage container and bone tissue regeneration substrate, etc. 12 By dissolving organic precursors of metal/metal oxide into the electrospinning PAN solution, CNF/M or CNF/MO x composites could be readily prepared.…”

Section: Introductionmentioning

confidence: 99%

“…[13][14][15]20,24 Wang et al reported that the size of Fe 3 O 4 nanoparticles in CNF/ Fe 3 O 4 composite increased remarkably along with higher sintering temperature. [13][14][15]20,24 Wang et al reported that the size of Fe 3 O 4 nanoparticles in CNF/ Fe 3 O 4 composite increased remarkably along with higher sintering temperature.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

et al. 2014

Self Cite

View full text Add to dashboard Cite

Polyacrylonitrile (PAN) electrospinning in combination with sol-gel method has been a common technique to produce inorganic nanoparticles containing composite carbon nanofibers (CNFs) for diverse applications. To investigate the morphology evolution and crystal transformation of inorganic components along with CNF formation, bioactive glass (BG) containing CNFs (CNF/BG) were prepared by sintering as-spun PAN/precursor composite nanofibers in a nitrogen atmosphere at temperatures of 800, 1000 and 1200 C. Comprehensive characterizations were performed with TEM, SEM-EDXA and XRD. For samples sintered at 800 C, numerous BG nanoparticles were observed inside the CNFs and mainly in an amorphous state. With the sintering temperature raised to 1000 C, a number of spherical BG nanoparticles were detected on the surface of the resulting CNFs, with a crystal structure of wollastonite (b-CaSiO 3 ) polycrystals. When the samples were sintered at 1200 C, the BG nanoparticles on the surface of CNFs merged into forms with cuboid-like geometry, mainly consisting of pseudowollastonite (Ca 3 (Si 3 O 9 )) single crystals. Based on the geometry evolution and dynamic size distribution function analyses (Ostwald ripening and Smoluchowski equations), it was concluded that the growth of BG nanoparticles conformed to the ripening mechanism at 800 C and migrationcoalescence mechanism at 1200 C, while the process involved both ripening and migrationcoalescence mechanisms at 1000 C.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

et al. 2014

Self Cite

View full text Add to dashboard Cite

show abstract

“…CNFs containing β-tricalcium phosphate nanoparticles have shown good biocompatibility for cell growth [95]. The results indicated that bioactive HA strongly interacted with the CNFs through coordination bonds and would provide strong interfacial bonding to host tissues.…”

Section: Biomedical Applicationmentioning

confidence: 99%

Hierarchical porous carbon nanofibers via electrospinning

Raza¹,

Wang²,

Yang³

et al. 2014

Carbon letters

View full text Add to dashboard Cite

Carbon nanofibers (CNFs) with diameters in the submicron and nanometer range exhibit high specific surface area, hierarchically porous structure, flexibility, and super strength which allow them to be used in the electrode materials of energy storage devices, and as hybrid-type filler in carbon fiber reinforced plastics and bone tissue scaffold. Unlike catalytic synthesis and other methods, electrospinning of various polymeric precursors followed by stabilization and carbonization has become a straightforward and convenient way to fabricate continuous CNFs. This paper is a comprehensive and brief review on the latest advances made in the development of electrospun CNFs with major focus on the promising applications accomplished by appropriately regulating the microstructural, mechanical, and electrical properties of as-spun CNFs. Additionally, the article describes the various strategies to make a variety of carbon CNFs for energy conversion and storage, catalysis, sensor, adsorption/separation, and biomedical applications. It is envisioned that electrospun CNFs will be the key materials of green science and technology through close collaborations with carbon fibers and carbon nanotubes.

show abstract

“…To produce hybridized CNF containing homogeneously distributed ceramic nanoparticles, a combination of ceramic precursor sol-gel and PAN electrospinning with subsequent stabilization and carbonization has been well developed1819. Reasonably, in our previous studies, bioceramic components including calcium phosphate (CaP) and bioactive glass (BG) had been incorporated into CNF by a similar way20212223. Compared to pure CNF, it was found CaP (CNF/CaP) or BG nanoparticle loaded CNF (CNF/BG) was able to accelerate apatite deposition in simulated body fluid (SBF) and to improve cell affinity, showing strong dependence on the chemical composition, morphology and crystalline structure of ceramic nanoparticles2123.…”

mentioning

confidence: 99%

Cell studies of hybridized carbon nanofibers containing bioactive glass nanoparticles using bone mesenchymal stromal cells

Zhang

Jia

et al. 2016

Sci Rep

Self Cite

View full text Add to dashboard Cite

Bone regeneration required suitable scaffolding materials to support the proliferation and osteogenic differentiation of bone-related cells. In this study, a kind of hybridized nanofibrous scaffold material (CNF/BG) was prepared by incorporating bioactive glass (BG) nanoparticles into carbon nanofibers (CNF) via the combination of BG sol-gel and polyacrylonitrile (PAN) electrospinning, followed by carbonization. Three types (49 s, 68 s and 86 s) of BG nanoparticles were incorporated. To understand the mechanism of CNF/BG hybrids exerting osteogenic effects, bone marrow mesenchymal stromal cells (BMSCs) were cultured directly on these hybrids (contact culture) or cultured in transwell chambers in the presence of these materials (non-contact culture). The contributions of ion release and contact effect on cell proliferation and osteogenic differentiation were able to be correlated. It was found that the ionic dissolution products had limited effect on cell proliferation, while they were able to enhance osteogenic differentiation of BMSCs in comparison with pure CNF. Differently, the proliferation and osteogenic differentiation were both significantly promoted in the contact culture. In both cases, CNF/BG(68 s) showed the strongest ability in influencing cell behaviors due to its fastest release rate of soluble silicium-relating ions. The synergistic effect of CNF and BG would make CNF/BG hybrids promising substrates for bone repairing.

show abstract

The biological properties of carbon nanofibers decorated with β-tricalcium phosphate nanoparticles

Cited by 27 publications

References 18 publications

Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

Growth mechanism of bioglass nanoparticles in polyacrylonitrile-based carbon nanofibers

Hierarchical porous carbon nanofibers via electrospinning

Cell studies of hybridized carbon nanofibers containing bioactive glass nanoparticles using bone mesenchymal stromal cells

Contact Info

Product

Resources

About