The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis

Niarchou, Maria; Zammit, Stanley; Lewis, Glyn

doi:10.1007/s00127-015-1072-8

Cited by 53 publications

(56 citation statements)

References 113 publications

(86 reference statements)

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“…Furthermore, parental separation can lead to residential moves, which for the children may entail entering a new school and having to make new friends in an already stressful situation [13]. Indeed, changing schools has been shown to be linked with an increased risk of adverse mental health [21]. Unsurprisingly, studies have shown that it is more common for individuals with separated parents to have moved during childhood [12, 18].…”

Section: Introductionmentioning

confidence: 99%

Parental separation in childhood as a risk factor for depression in adulthood: a community-based study of adolescents screened for depression and followed up after 15 years

et al. 2017

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BackgroundEarlier research has investigated the association between parental separation and long-term health outcomes among offspring, but few studies have assessed the potentially moderating role of mental health status in adolescence. The aim of this study was to analyze whether parental separation in childhood predicts depression in adulthood and whether the pattern differs between individuals with and without earlier depression.MethodsA community-based sample of individuals with adolescent depression in 1991–93 and matched non-depressed peers were followed up using a structured diagnostic interview after 15 years. The participation rate was 65% (depressed n = 227; non-depressed controls n = 155). Information on parental separation and conditions in childhood and adolescence was collected at baseline. The outcome was depression between the ages 19–31 years; information on depression was collected at the follow-up diagnostic interview. The statistical method used was binary logistic regression.ResultsOur analyses showed that depressed adolescents with separated parents had an excess risk of recurrence of depression in adulthood, compared with depressed adolescents with non-separated parents. In addition, among adolescents with depression, parental separation was associated with an increased risk of a switch to bipolar disorder in adulthood. Among the matched non-depressed peers, no associations between parental separation and adult depression or bipolar disorder were found.ConclusionsParental separation may have long-lasting health consequences for vulnerable individuals who suffer from mental illness already in adolescence.

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Section: Introductionmentioning

confidence: 99%

Parental separation in childhood as a risk factor for depression in adulthood: a community-based study of adolescents screened for depression and followed up after 15 years

et al. 2017

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“…The importance of assessing functioning across this broader range of developmental domains is underscored by longitudinal prospective cohort investigations (e.g. Niarchou et al 2015; Poulton et al 2015), which demonstrate that early childhood difficulties in behavioural, emotional, social, cognitive and physical functioning are risk factors for a variety of adverse adolescent and adult outcomes beyond juvenile delinquency and adult offending, including mental and physical illnesses, social maladjustment, and poor educational and occupational outcomes.…”

Section: Introductionmentioning

confidence: 99%

Pervasive influence of maternal and paternal criminal offending on early childhood development: a population data linkage study

et al. 2016

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BackgroundParental criminal offending is an established risk factor for offending among offspring, but little evidence is available indicating the impact of offending on early childhood functioning. We used data from a large Australian population cohort to determine associations between exposure to parental offending and a range of developmental outcomes at age 5 years.MethodMulti-generation data in 66 477 children and their parents from the New South Wales Child Development Study were combined using data linkage. Logistic and multinomial regressions tested associations between any and violent offending histories of parents (fathers, mothers, or both parents) obtained from official records, and multiple measures of early childhood developmental functioning (social, emotional–behavioural, cognitive, communication and physical domains) obtained from the teacher-reported 2009 Australian Early Development Census.ResultsParental offending conferred significantly increased risk of vulnerability on all domains, particularly the cognitive domain. Greater risk magnitudes were observed for offending by both parents and by mothers than by fathers, and for violent than for any offending. For all parental offending exposures, vulnerability on multiple domains (where medium to large effects were observed) was more likely than on a single domain (small to medium effects). Relationships remained significant and of comparable magnitude following adjustment for sociodemographic covariates.ConclusionsThe effect of parental offending on early childhood developmental outcomes is pervasive, with the strongest effects on functioning apparent when both parents engage in violent offending. Supporting affected families in early childhood might mitigate both early developmental vulnerability and the propensity for later delinquency among these offspring.

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“…to account for attrition in cohort studies (Niarchou et al, 2015, Sterne et al, 2009 (Fagan, 2014, Niarchou et al, 2015. These findings, if replicated…”

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confidence: 62%

Does father–child conflict mediate the association between fathers’ postnatal depressive symptoms and children's adjustment problems at 7 years old?

et al. 2016

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Paternal depressive symptoms are associated with children's emotional and behavioural 29 problems, which may be mediated by negative parenting. But there is no research on the influence of paternal 30 depressive symptoms on children's emotion regulation and limited literature investigating fathers' parenting as a 31 mediator in the pathway between paternal depressive symptoms and children's externalising and internalising 32 problems. We aimed to investigate the mediating role of father-child conflict (at 3 years) in the association 33 between postnatal paternal depressive symptoms (at 9-months) and children's emotional and behavioural (at 7 34 years) (aim 1). We also examined whether mediation pathways were more pronounced for boys or for girls (aim 35 2). 36Methods: Secondary data analysis was conducted on the Millennium Cohort Study, when children were 9-37 months, 3-years and 7-years-old (n=3,520). Main study variables were measured by self-report questionnaires.

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The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis

Cited by 53 publications

References 113 publications

Parental separation in childhood as a risk factor for depression in adulthood: a community-based study of adolescents screened for depression and followed up after 15 years

Parental separation in childhood as a risk factor for depression in adulthood: a community-based study of adolescents screened for depression and followed up after 15 years

Pervasive influence of maternal and paternal criminal offending on early childhood development: a population data linkage study

Does father–child conflict mediate the association between fathers’ postnatal depressive symptoms and children's adjustment problems at 7 years old?

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