The Association of Dietary Cholesterol from Egg Consumption on Cardiovascular Diseases Risk Varies from Person to Person

Zhang, Fan; Li, Junhua; Chang, Cuihua; Gu, Luping; Xiong, Wen Cheng; Su, Yujie; Yang, Yanjun

doi:10.1021/acs.jafc.2c04634

Cited by 5 publications

(3 citation statements)

References 120 publications

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“…To understand the overall findings, it is important to differentiate individual health status and cholesterol sensitivity, dietary patterns, region, and ethnicity. Additionally, a moderate intake of high-cholesterol foods, such as eggs, was found to have no substantial effect on cholesterol homeostasis in healthy individuals [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

Associations between Cholesterol Intake, Food Sources and Cardiovascular Disease in Chinese Residents

Cao,

2024

Nutrients

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Cholesterol is a nutrient commonly found in the human diet. The relationship between dietary cholesterol, its sources, and cardiovascular disease (CVD) is still a topic of debate. This study aimed to investigate the association between dietary cholesterol, its sources, and cardiovascular events in a Chinese population. The present study analyzed data from the China Health and Nutrition Survey (CHNS) cohort between 1991 and 2015. This study analyzed data from 3903 participants who were 40 years of age or older at baseline and had no history of cardiovascular disease, diabetes, or hypertension. During a median follow-up of 14 years, 503 cardiovascular disease events were identified through follow-up questionnaires administered every 2–3 years. The events included fatal and nonfatal coronary heart disease, stroke, heart failure, and other cardiovascular disease deaths. Cox regression was used to estimate risk ratios (HR) for CVD events after adjusting for demographic, socioeconomic, and behavioral factors. It was discovered that sources of dietary cholesterol varied among different subgroups of the population. The top three sources of cholesterol among all participants were eggs, red meat, and seafood, accounting for 57.4%, 28.2%, and 9.0% of total daily cholesterol intake, respectively. The present study found that there was a significant association between total dietary cholesterol intake, and the risk of developing cardiovascular disease (adjusted HR [95% CI]: total cholesterol (highest and lowest quartiles compared) 1.57 [1.17–2.11]). Cholesterol from poultry, seafood, and eggs was also significantly associated with a reduced risk of CVD (adjusted HR [95% CI]: poultry 0.18 [0.04–0.82], seafood 0.11 [0.02–0.54], and eggs 0.16 [0.03–0.73]). After adjusting for daily caloric intake, daily fat intake, and daily saturated fat intake, the previously observed association between red meat cholesterol and cardiovascular events (unadjusted HR [95% CI]: 0.44 [0.35–0.55]) was no longer statistically significant (adjusted HR [95% CI]: 0.21 [0.04–1.01]).

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Section: Discussionmentioning

confidence: 99%

Associations between Cholesterol Intake, Food Sources and Cardiovascular Disease in Chinese Residents

Cao,

2024

Nutrients

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“…These nutrients are critical for maintaining strong bones, and their presence in eggs underscores the potential benefits of egg consumption [3,4,[8][9][10]. Historically, whole eggs have faced scrutiny due to their high cholesterol content, and concerns about their impact on cardiovascular health have been the subject of research [11][12][13][14]. However, recent studies have challenged this notion, suggesting that moderate egg consumption may not significantly increase the risk of heart disease [13,14].…”

Section: Introductionmentioning

confidence: 99%

“…Historically, whole eggs have faced scrutiny due to their high cholesterol content, and concerns about their impact on cardiovascular health have been the subject of research [11][12][13][14]. However, recent studies have challenged this notion, suggesting that moderate egg consumption may not significantly increase the risk of heart disease [13,14]. Yet, the specific associations between habitual egg consumption and bone health remain relatively uncharted in nutrition research.…”

Section: Introductionmentioning

confidence: 99%

Egg consumption and bone mass density among the elderly: A scoping review

Olagunju,

Abodunrin,

Omotoso

et al. 2024

PLOS Glob Public Health

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Eggs offer a range of essential nutrients that could support skeletal health as individuals age. Maintaining bone density is crucial for reducing the risk of fractures and improving overall mobility and quality of life in later years. Understanding the potential benefits of habitual egg consumption on bone mass density among older people is essential, given that the natural decline in bone mass density occurs with age. This area of research has not garnered sufficient attention basically because of the mixed reactions and conflicting reports about the safety of egg consumption especially among the older adults. This scoping review aims to systematically examine the existing literature to map the evidence regarding the association between habitual egg consumption and bone mass density in older adults’ individuals. The scoping review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines to ensure methodological rigor and transparency. Five electronic databases were searched for published pieces of literature. While high egg intake has been linked to increased mortality and dyslipidemia, eggs contain compounds like Ovo transferrin and carotenoids that may benefit bone health. As aging increases vulnerability to bone fragility and fractures, it’s crucial to provide comprehensive dietary recommendations. The complex relationship between egg consumption, cholesterol, and health highlights the need for nuanced assessment. Overall, eggs present a potentially valuable dietary component for promoting bone health in aging populations. Limited research on the link between egg consumption and bone mass density in older adults highlights the need for further investigation. Concerns about cholesterol have overshadowed potential benefits. Given aging populations and bone health challenges, exploring eggs’ role in preventing falls and fractures is essential for a proactive approach to older adults’ well-being.

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Differential effects of egg consumption on fecal lipid metabolism: Insights from C57BL/6J mice under chow diet and high-fat diet

Zhang,

Yang,

et al. 2024

Food Bioscience

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The Association of Dietary Cholesterol from Egg Consumption on Cardiovascular Diseases Risk Varies from Person to Person

Cited by 5 publications

References 120 publications

Associations between Cholesterol Intake, Food Sources and Cardiovascular Disease in Chinese Residents

Associations between Cholesterol Intake, Food Sources and Cardiovascular Disease in Chinese Residents

Egg consumption and bone mass density among the elderly: A scoping review

Differential effects of egg consumption on fecal lipid metabolism: Insights from C57BL/6J mice under chow diet and high-fat diet

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