The Association of Chlamydia pneumoniae Infection and Reactive Airway Disease in Children

Importance of acute Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with wheezing

“…In agreement with previous reports, the present results also show that, in children with wheezing, the incidence of acute M. pneumoniae and C. pneumoniae infection increases with age and occurs mainly after 5 yrs of age [8,9]. Moreover, in the present study population, the incidence of asymptomatic infection in healthy subjects seemed to be low and was similar to that recently reported in adults [23,24].…”

Prevalence of Asymptomatic Infection With Chlamydia pneumoniae in Subjectively Healthy Adults

“…Our results are consistent with those reported by Gaydos et al 12 and Hyman et al 13 and indicate that asymptomatic upper respiratory tract infection due to C pneumoniae occurs in other healthy populations. However, the prevalence judged by our cell cultures was much lower than that reported by Gnarpe et al, 9 Emre et al, 10 and Block et al 11 (0.4% vs 4.7 to 5.0%). The difference may be because of the use of a different cohort from a different geographic area than that employed in their study.…”

Is There an Association between Kawasaki Disease andChlamydia pneumoniae?

“…In contrast to the study of Numazaki et al [6], anti-C. pneumoniae IgM was present in only 3%-4% of both cases and controls; however, this finding may not rule out C. pneumoniae infection, because, as we have reported elsewhere, 150% of children with culture-documented C. pneumoniae respiratory tract infection do not have detectable anti-C. pneumoniae antibodies, by MIF [3,4,8]. Two of 13 controls from Kings County Hospital were culture positive for C. pneumoniae: one was seronegative by MIF, and the other had an IgG titer of 1 : 256.…”