The association between adverse events of COVID-19 vaccination and anxiety and willingness to receive a booster dose

Chen, Liling; Liang, Hongyu; Liu, Li; Qiu, W.; Su, Liuhui; Yang, Haomin

doi:10.1080/21645515.2023.2176643

Cited by 2 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the evaluation of the effect of vaccination against COVID-19 on emotional health could be affected by the perception of the vaccine's effectiveness or worries about adverse events. 62 Older adults are particularly susceptible to fake news or misinformation, 63 which could influence their perception of vaccination against COVID-19 and diminish its effect on their mental health. This effect should be evaluated in future studies.…”

Section: Summary Of Resultsmentioning

confidence: 99%

Effects of vaccination against COVID-19 on the emotional health of older adults

et al. 2023

View full text Add to dashboard Cite

Background: The COVID-19 pandemic significantly impacted the mental and emotional health of the elderly, especially those from low to middle-income countries. However, COVID-19 vaccination may reduce this influence. Therefore, we aimed to estimate the effect of vaccination against COVID-19 on the emotional health of older adults. Methods: We selected a national, random, and stratified sample of non-hospitalized adults aged 60 to 79 years from Peru who intended to receive or had already received the COVID-19 vaccine during recruitment. During June and July 2021, the assessed outcomes were fear, anxiety, and worry about COVID-19, general anxiety, and depression at baseline and after a month. We estimated the adjusted odds ratios (aOR) and 95% confidence intervals (95% CI) for each altered emotional health outcome in those who had one and two doses, compared with those who were not vaccinated using multilevel logistic regression with mixed effects. Results: We recruited 861 older adults with 20.8% of loss to follow-up. At baseline, 43.9% had received only one dose of the vaccine, and 49.1% had two doses. In the analysis during follow-up, those who had two doses had less fear (aOR: 0.19; CI 95%: 0.07 to 0.51) and anxiety to COVID-19 (aOR: 0.45; CI 95%: 0.22 to 0.89), compared to unvaccinated. Also, those with two doses were significantly less likely to have fear of COVID-19 (aOR: 0.35; CI 95%: 0.21 to 0.59), anxiety about COVID-19 (aOR: 0.48; CI 95%: 0.34 to 0.68), and worry about COVID-19 (aOR: 0.58; CI 95%: 0.37 to 0.94), compared to those who had only one dose. We observed no effects in those with only one dose compared to unvaccinated. Conclusions: Two doses of COVID-19 vaccination in older adults improves their perception of COVID-19 infection consequences. This information could be integrated into the vaccination campaign as an additional beneficial effect.

show abstract

Section: Summary Of Resultsmentioning

confidence: 99%

Effects of vaccination against COVID-19 on the emotional health of older adults

et al. 2023

View full text Add to dashboard Cite

show abstract

Questionnaire-based study of COVID-19 vaccination induced headache: evidence of clusters of adverse events

Zhou,

Eggert,

Zhelyazkova

et al. 2024

BMC Neurol

View full text Add to dashboard Cite

Background The adverse events (AEs) after a Coronavirus disease 2019 (Covid-19) Pfizer-Biotech mRNA vaccination present a medical and epidemiological issue of increasing interest. Headache is the most frequent neurological adverse effect and generally the third most common adverse event after a Covid-19 vaccination, but only a few studies focus on the link between headache and other AEs after vaccination. This study aims to investigate the correlation between headaches and Covid-19 vaccination, as well as the possible links between headaches and other AEs after Covid-19 vaccination, thereby helping the management of AEs and avoiding further occurrences. Methods This study is based on a published questionnaire survey of 1,402 healthcare workers. Our study focused on the 5 questions including 12 AEs and headaches extracted from the questionnaire post the first and second Covid-19 vaccination. The severity of the 12 AEs and headaches could be classified by the participants on a five-step scale: “Not at all”, “Little”, “Average”, “Quite”, and “Very” (abbreviated as “N”, “L”, “A”, “Q”, “V”). We used the Bowker test to study the comparison of headache severity, indicated on a 5-point Likert scale between the first and second vaccinations. We applied an ordinal logistic regression to the 5 categories with headache severity serving as the dependent variable and the ratings of the other 12 AEs serving as the independent variable to further explore to what extent the severity of the 12 AEs is associated with the severity of headaches. Receiver Operating Characteristic (ROC) analysis was conducted to evaluate the predictive value of the ratings of the 12 AEs to headache severity. Results We found that participants rated their headaches as more severe after the second vaccination, and participants who reported experiencing fatigue, flu-like symptoms, pain at the injection site, known tension-type headache, fever, dizziness/balance problems and known migraine are associated with headache symptoms. Conclusions There are clusters of headache-associated AEs post Covid-19 vaccination. The association of various AEs with headaches may be due to similar causative mechanisms.

show abstract

The association between adverse events of COVID-19 vaccination and anxiety and willingness to receive a booster dose

Cited by 2 publications

References 9 publications

Effects of vaccination against COVID-19 on the emotional health of older adults

Effects of vaccination against COVID-19 on the emotional health of older adults

Questionnaire-based study of COVID-19 vaccination induced headache: evidence of clusters of adverse events

Contact Info

Product

Resources

About