The Arginine Requirement of the Infant

Evidence that histidine is an essential amino acid in normal and chronically uremic man.

“…It is of interest that Snyderman, Boyer, Roitman, Holt, and Prose noted that infants fed histidine-deficient diets developed a skin lesion similar to that observed in the present study (2). They suggested that the eruption may be due to low histamine levels in skin, and this lesion may therefore represent a specific response to histidine deficiency.…”

Evidence that histidine is an essential amino acid in normal and chronically uremic man.

“…It is of interest that Snyderman, Boyer, Roitman, Holt, and Prose noted that infants fed histidine-deficient diets developed a skin lesion similar to that observed in the present study (2). They suggested that the eruption may be due to low histamine levels in skin, and this lesion may therefore represent a specific response to histidine deficiency.…”

Gyrate atrophy of the choroid and retina: amino acid metabolism and correction of hyperornithinemia with an arginine-deficient diet.

“…Conversion of glutamate to ornithine has recently been reported to occur in rat intestinal homogenates (31), presumably through the OAT reaction. This pathway must explain the apparent nonessentiality of arginine in man (32)(33)(34). Those animals in which arginine is essential or semiessential must not be able to achieve the conditions required for adequate reverse flux through the OAT reaction.…”

Free Amino Acid Levels of Mother and Child Immediately after Delivery in Dar es Salaam, Tanzania

“…Therefore, the interpretation of our values in comparison with other studies, like for Sweden (11), have to be carried out with caution. In this study certain amino acids like histidine, cystine, tyrosine and probably taurine were regarded as non-essential although some studies have demonstrated that these amino acids may be essential in utero (5,10,23,26).…”

Evidence that histidine is an essential amino acid in normal and chronically uremic man.

“…It is of interest that Snyderman, Boyer, Roitman, Holt, and Prose noted that infants fed histidine-deficient diets developed a skin lesion similar to that observed in the present study (2). They suggested that the eruption may be due to low histamine levels in skin, and this lesion may therefore represent a specific response to histidine deficiency.…”

Gyrate atrophy of the choroid and retina: amino acid metabolism and correction of hyperornithinemia with an arginine-deficient diet.

“…Conversion of glutamate to ornithine has recently been reported to occur in rat intestinal homogenates (31), presumably through the OAT reaction. This pathway must explain the apparent nonessentiality of arginine in man (32)(33)(34). Those animals in which arginine is essential or semiessential must not be able to achieve the conditions required for adequate reverse flux through the OAT reaction.…”

Free Amino Acid Levels of Mother and Child Immediately after Delivery in Dar es Salaam, Tanzania

“…Therefore, the interpretation of our values in comparison with other studies, like for Sweden (11), have to be carried out with caution. In this study certain amino acids like histidine, cystine, tyrosine and probably taurine were regarded as non-essential although some studies have demonstrated that these amino acids may be essential in utero (5,10,23,26).…”

Evidence that histidine is an essential amino acid in normal and chronically uremic man.

“…It is of interest that Snyderman, Boyer, Roitman, Holt, and Prose noted that infants fed histidine-deficient diets developed a skin lesion similar to that observed in the present study (2). They suggested that the eruption may be due to low histamine levels in skin, and this lesion may therefore represent a specific response to histidine deficiency.…”

Gyrate atrophy of the choroid and retina: amino acid metabolism and correction of hyperornithinemia with an arginine-deficient diet.

“…Conversion of glutamate to ornithine has recently been reported to occur in rat intestinal homogenates (31), presumably through the OAT reaction. This pathway must explain the apparent nonessentiality of arginine in man (32)(33)(34). Those animals in which arginine is essential or semiessential must not be able to achieve the conditions required for adequate reverse flux through the OAT reaction.…”

Free Amino Acid Levels of Mother and Child Immediately after Delivery in Dar es Salaam, Tanzania

“…Therefore, the interpretation of our values in comparison with other studies, like for Sweden (11), have to be carried out with caution. In this study certain amino acids like histidine, cystine, tyrosine and probably taurine were regarded as non-essential although some studies have demonstrated that these amino acids may be essential in utero (5,10,23,26).…”