Journal of Cell Biology volume 217, issue 3, P1047-1062 2018 DOI: 10.1083/jcb.201705107 View full text
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Elodie Forest, Rémi Logeay, Charles Géminard, Diala Kantar, Florence Frayssinoux, Lisa Heron-Milhavet, Alexandre Djiane

Abstract: During development, cell proliferation is regulated, ensuring that tissues reach their correct size and shape. Forest et al. show that the Drosophila melanogaster scaffold protein big bang (Bbg) controls epithelial tissue growth without affecting epithelial polarity and architecture. Bbg interacts with spectrins at the apical cortex and promotes Yki signaling and actomyosin contractility.