The anxiolytic effects of intravenous sedation using midazolam alone or in multiple drug techniques

The Anxiolytic Effect of Midazolam in Third Molar Extraction: A Systematic Review

“…Two double-blind controlled studies [ 10 , 15 ] examined 4 drug combinations (midazolam, midazolam-midazolam, fentanyl-midazolam, and fentanyl-midazolam-methohexital). One study [ 15 ] included 207 participants (57% women, mean age 25.7 ± 5.3 years), and another [ 10 ] included 985 participants (532 men, 453 women). Two additional articles [ 18 , 19 ], similar to the two included articles, were excluded, but their data were useful.…”

The Anxiolytic Effect of Midazolam in Third Molar Extraction: A Systematic Review

“…Two double-blind controlled studies [ 10 , 15 ] examined 4 drug combinations (midazolam, midazolam-midazolam, fentanyl-midazolam, and fentanyl-midazolam-methohexital). One study [ 15 ] included 207 participants (57% women, mean age 25.7 ± 5.3 years), and another [ 10 ] included 985 participants (532 men, 453 women). Two additional articles [ 18 , 19 ], similar to the two included articles, were excluded, but their data were useful.…”

Different Uses of Conscious Sedation for Managing Dental Anxiety During Third-Molar Extraction: Clinical Evidence and State of the Art

“…48,49 However, the type of distraction technique used was only sometimes provided. 50,51 In addition, few studies have focused on the patient's sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view. 52,53 Non-VR content creates less immersion because the user is limited in all these virtual movements.…”

“…The studies of this systematic review and meta-analysis differ in statistical quality—most used randomization by clearly establishing inclusion and exclusion criteria 48,49 . However, the type of distraction technique used was only sometimes provided 50,51 . In addition, few studies have focused on the patient’s sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view 52,53 .…”

Psycho‐social perspectives of nonsurgical versus surgical endodontic interventions in persistent endodontic disease

“…Patients who experience greater anxiety have been found to be more likely to encounter moderate or intense intra‐operative pain (Murillo‐Benítez et al, 2020). Studies have found that anxiolytic drugs provided before dental treatment can be effective in controlling fear and intra‐operative pain, with mild adverse effects encountered (Milgrom et al, 1994; Nutt et al, 2009). However, there is a low level of awareness amongst patients regarding options for sedation (Huh et al, 2015) and a lack of training amongst dentists on administration (Yehia et al, 2018).…”

The Anxiolytic Effect of Midazolam in Third Molar Extraction: A Systematic Review

“…Two double-blind controlled studies [ 10 , 15 ] examined 4 drug combinations (midazolam, midazolam-midazolam, fentanyl-midazolam, and fentanyl-midazolam-methohexital). One study [ 15 ] included 207 participants (57% women, mean age 25.7 ± 5.3 years), and another [ 10 ] included 985 participants (532 men, 453 women). Two additional articles [ 18 , 19 ], similar to the two included articles, were excluded, but their data were useful.…”

Different Uses of Conscious Sedation for Managing Dental Anxiety During Third-Molar Extraction: Clinical Evidence and State of the Art

“…48,49 However, the type of distraction technique used was only sometimes provided. 50,51 In addition, few studies have focused on the patient's sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view. 52,53 Non-VR content creates less immersion because the user is limited in all these virtual movements.…”

“…The studies of this systematic review and meta-analysis differ in statistical quality—most used randomization by clearly establishing inclusion and exclusion criteria 48,49 . However, the type of distraction technique used was only sometimes provided 50,51 . In addition, few studies have focused on the patient’s sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view 52,53 .…”

Psycho‐social perspectives of nonsurgical versus surgical endodontic interventions in persistent endodontic disease

“…Patients who experience greater anxiety have been found to be more likely to encounter moderate or intense intra‐operative pain (Murillo‐Benítez et al, 2020). Studies have found that anxiolytic drugs provided before dental treatment can be effective in controlling fear and intra‐operative pain, with mild adverse effects encountered (Milgrom et al, 1994; Nutt et al, 2009). However, there is a low level of awareness amongst patients regarding options for sedation (Huh et al, 2015) and a lack of training amongst dentists on administration (Yehia et al, 2018).…”

The Anxiolytic Effect of Midazolam in Third Molar Extraction: A Systematic Review

“…Two double-blind controlled studies [ 10 , 15 ] examined 4 drug combinations (midazolam, midazolam-midazolam, fentanyl-midazolam, and fentanyl-midazolam-methohexital). One study [ 15 ] included 207 participants (57% women, mean age 25.7 ± 5.3 years), and another [ 10 ] included 985 participants (532 men, 453 women). Two additional articles [ 18 , 19 ], similar to the two included articles, were excluded, but their data were useful.…”

Different Uses of Conscious Sedation for Managing Dental Anxiety During Third-Molar Extraction: Clinical Evidence and State of the Art

“…48,49 However, the type of distraction technique used was only sometimes provided. 50,51 In addition, few studies have focused on the patient's sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view. 52,53 Non-VR content creates less immersion because the user is limited in all these virtual movements.…”

“…The studies of this systematic review and meta-analysis differ in statistical quality—most used randomization by clearly establishing inclusion and exclusion criteria 48,49 . However, the type of distraction technique used was only sometimes provided 50,51 . In addition, few studies have focused on the patient’s sensitivity to VR; an important element to be analyzed is the immersion of the patient in VR, which is influenced by the interaction of the subject with the virtual environment through virtual physical movements such as position change, orientation change, and point of view 52,53 .…”

Psycho‐social perspectives of nonsurgical versus surgical endodontic interventions in persistent endodontic disease

“…Patients who experience greater anxiety have been found to be more likely to encounter moderate or intense intra‐operative pain (Murillo‐Benítez et al, 2020). Studies have found that anxiolytic drugs provided before dental treatment can be effective in controlling fear and intra‐operative pain, with mild adverse effects encountered (Milgrom et al, 1994; Nutt et al, 2009). However, there is a low level of awareness amongst patients regarding options for sedation (Huh et al, 2015) and a lack of training amongst dentists on administration (Yehia et al, 2018).…”