2006
DOI: 10.1007/s11547-006-0032-5
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Abstract: Mediastinal tumours are frequently asymptomatic and first noted on routine chest radiograph. In most cases, evaluation should proceed to spiral computed tomography (sCT) of the chest with iodinated contrast material. The specific location and appearance of tumours on sCT is instrumental in planning further diagnostic and treatment strategies. Primary tumours in the anterior mediastinum account for half of all mediastinal masses. They comprise various benign and malignant neoplasms, but a wide variety of nonneo… Show more

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Cited by 61 publications
(77 citation statements)
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“…16 Diagnostic imaging is crucial in all patients affected by MG for evaluating the presence of an underlying TLH or THY and for distinguishing these two conditions in order to select the proper therapeutic management, because the treatment strategies are different. 2,16,17 Indeed, surgery is strongly recommended in patients with THY and represents the mainstay of the curative-intent treatment, since complete resection is the most significant positive prognostic factor, both on disease-free and overall survival. 18 Conversely, in non-thymomatous MG, the primary therapeutic management is based on the use of acetylcholinesterase inhibitors and immunomodulatory agents.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…16 Diagnostic imaging is crucial in all patients affected by MG for evaluating the presence of an underlying TLH or THY and for distinguishing these two conditions in order to select the proper therapeutic management, because the treatment strategies are different. 2,16,17 Indeed, surgery is strongly recommended in patients with THY and represents the mainstay of the curative-intent treatment, since complete resection is the most significant positive prognostic factor, both on disease-free and overall survival. 18 Conversely, in non-thymomatous MG, the primary therapeutic management is based on the use of acetylcholinesterase inhibitors and immunomodulatory agents.…”
Section: Discussionmentioning
confidence: 99%
“…Unfortunately, there is no perfect correlation among Jeong and Masaoka-Koga classifications because, although low-risk thymomas are frequently grouped in the earlydisease group, percentages of high-risk thymomas are reported at a rate up to 45 % in the early stage disease group [10]. Limited data are available on quantitative assessment of thymic epithelial tumours (TETs) by using diffusionweighted magnetic resonance imaging (DW-MRI) from small cohorts of studies which considered various anterior mediastinal tumours, although those studies did not attempt to differentiate thymomas based on WHO and MasaokaKoga classifications by using the ADC [11][12][13][14][15][16][17][18]. More recently, a study involving 30 patients with TETs has demonstrated the ability of ADC in differentiating low-risk from high-risk tumours, and early from advanced disease [19].…”
Section: Introductionmentioning
confidence: 99%
“…Malign teratomada anjiyosarkoma, rabdomyosarkoma, adenokarsinoma veya squamöz hücreli karsinoma içeren malign dokular bulunur. Prognoz çocukluk çağında oldukça iyi iken, ileri yaş grubunda kötüdür (38,40).…”
Section: Germ Hücreli Tümörlerunclassified
“…BT'de büyük, irregüler, heterojen dansitede kitleler olarak izlenirler. α-FP, β-HCG gibi tümör markırları genellikle yüksektir (38,40).…”
Section: Germ Hücreli Tümörlerunclassified
“…Primary anterior mediastinal tumors account for 50% of mediastinal tumors, including thymic hyperplasia, thymoma, thymic cysts, mature type and immature type teratomas, germ cell tumors and lymphoma, however, thymoma is the most common primary tumor of the anterior mediastinum (1)(2)(3)(4). At present, morphological examinations including computed tomography (CT) and magnetic resonance imaging (MRI) are advantageous in that they are able to identify the anatomical locations of tumors and their relationships with adjacent tissues and organs.…”
Section: Introductionmentioning
confidence: 99%