The Akut Toxicity Testing Lethal Dose Oral Green Meniran Leaf Extract by Using Mice
Ni Kadek Eka Widiadnyani,
Luh Made Sudimartini
Abstract:The use of a dose limit of green meniran leaf extract (Phylanthus niruri Linn) must be known for its safety which is supported by research results. The aims of this research to determine the acute lethal dose (LD50) toxicity and to examine the macropathological changes in the vital organs of mice. A total of 30 male mice and 30 female mice were divided into five groups and six replicates. Experimental mice in the control group (K) were given 0.9% NaCl, while those given meniran extract at doses of 50, 300, 20… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.