2020
DOI: 10.1101/2020.03.26.010363
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Joshua Rees-Garbutt, Jake Rightmyer, Oliver Chalkley et al.

Abstract: Numerous authors have pondered what the minimal gene set for life might be and many hypothetical minimal gene sets have been proposed, including at least 10 for Mycoplasma genitalium (M.genitalium) . None of these have been reported to be tested in-vivo or in-silico . In-vivo testing would be extremely difficult as M.genitalium is very difficult to grow in the laboratory and laborious to engineer. However, the M.genitalium whole-cell model provides the first opportunity to test them in-silico . We simulated t…

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