Ternary polymer blends: prediction of mechanical properties for various phase structures

Abstract

The relative bioavailability of clomipramine was determined in two single‐blind, single‐dose, randomized, crossover studies. In the first study, the relative bioavailability of the test product, 2×25 mg clomipramine hydrochloride tablets (Noristan Ltd.), with respect to the reference product, Anafranil® 2×25 mg tablets (clomipramine HCl; Ciba—Geigy (Pty) Ltd.) was determined. In the second study, the relative bioavailability of the test product, 5×10 mg clomipramine hydrochloride tablets (Noristan Ltd.), with respect to the reference product, Anafranil® 5×10 mg tablets (clomipramine HCl; Ciba—Geigy (Pty) Ltd.), was determined. The geometric mean values for the variable Cmax were 31·.3 ng mL−1 for the reference and 31·.6 ng mL−1 for the test product in study 1. The geometric mean values for the variable AUC were 736 ng h mL−1 and 753 ng h mL−1 for the reference and test, respectively. In study 2, the geometric mean Cmax values were 25·.8 ng mL−1 and 23·.9 ng mL−1 for the reference and test respectively; the geometric mean AUC values were 569 ng h mL−1 and 547 ng h mL−1. The 90% confidence intervals for the ‘test/reference’ mean ratios of the plasma clomipramine pharmacokinetic variables Cmax and AUC(0–∞) (as measures of the rate and extent of absorption of clomipramine, respectively) fall within the conventional bioequivalence range of 80–125% for both studies. The test products (clomipramine HCl) are therefore bioequivalent to the reference products (Anafranil®) with respect to the rate and the extent of absorption of clomipramine in both 10 mg and 25 mg strengths.

Correlating miscibility, mechanical parameters, and stability of ternary polymer blends for high-performance solar cells

“…27,29,31,52 In conventional polymer engineering, the third component is used as a compatibilizer in an immiscible system to enhance the interfacial adhesion if it is miscible with each of the other polymers. 25,53 However, when the third component is just miscible with one of the polymers or immiscible with both polymers, there is a lack of in-depth research, especially for the active layer of all-PSCs. The Flory–Huggins interaction parameter χ is important for the quantitative description and prediction of the miscibility of polymer blends.…”

“…The immiscible polymer systems tend to form separate pure phase components and large phase separations, while the miscible polymer systems tend to form uniform co-continuous structures. 25,53 Having understood the crystalline properties, morphology, thermodynamic properties and structure types of ternary blends, we attempted to relate them with thermal stability and mechanical properties. Highly miscible polymer blends hinder the crystallization of polymer donors and acceptors in blends, especially under prolonged thermal stress, resulting in better thermal stability.…”

Use of SEBS/EPR and SBR/EPR as Binary Compatibilizers for PE/PP/PS/HIPS Blends: A Work Oriented to the Recycling of Thermoplastic Wastes

“…Where v i is the volume fraction of the inclusions; A i , B i and P i are constants;12, 40 S y m is the yield stress of the matrix, v f is the volume fraction of the dispersed material and v f max is the maximum fraction of the dispersed material.…”

Synergistic optimization of mechanical and photovoltaic properties in ternary organic solar cells from a two-donor polymer blend

“…We noted that the equivalent box model (EBM) was used to predict the elastic modulus of multicomponent polymer systems. 22,[54][55][56][57][58] This motivated us to understand the ternary OSC systems with the EBM. As shown in Fig.…”