Tender linear lesions of the fingers. Acrokeratoelastoidosis (acquired type) or degenerative collagenous plaques of the hands

Cm, Parker

doi:10.1001/archderm.127.1.114

Cited by 9 publications

(6 citation statements)

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“…AKE is a rare disorder that commonly presents during childhood or adolescence, although presentation in adulthood (ages 54e77 years) has also been reported. 148,149 There appears to be no racial or ethnic predilection. 150 Etiology and pathogenesis.…”

Section: Acrokeratoelastoidosismentioning

confidence: 99%

“…146 In addition to presumptively acquired cases, both sporadic and autosomal dominant forms of AKE have been reported. 146,148,[151][152][153][154][155] There is some evidence to suggest that the pathogenesis of AKE may be due to a failure of elastic fiber synthesis rather than degeneration. Results of an ultrastructural study showed that fibroblasts of lesional skin contain dense granules at the periphery of their cytoplasm, while extracellular elastic fibers are deficient; such findings are consistent with a defect in the secretion of elastic material.…”

Section: Acrokeratoelastoidosismentioning

confidence: 99%

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Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Lewis

Bercovitch

Dill

et al. 2004

Journal of the American Academy of Dermatology

170

216

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Section: Acrokeratoelastoidosismentioning

confidence: 99%

Section: Acrokeratoelastoidosismentioning

confidence: 99%

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Lewis

Bercovitch

Dill

et al. 2004

Journal of the American Academy of Dermatology

170

216

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“…On the basis of its unique clinical and histologic characteristics, Costa named this distinct entity acrokeratoelastoidosis (AKE). Since his description of AKE, several cases have been reported with the typical clinical and histologic features (2–11).…”

mentioning

confidence: 99%

Acrokeratoelastoidosis

Cook

Vicki

et al. 2002

Pediatric Dermatology

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Acrokeratoelastoidosis of Costa is a rare papular palmoplantar keratosis characterized by small round-oval to rhomboid-shaped, yellowish papules most commonly localized to the palmar surface of the hands and sometimes also found on plantar surfaces of the feet. Both autosomal dominant and sporadic forms of the disease have been reported. Histologically acrokeratoelastoidosis is marked by hyperkeratosis and epidermal hypertrophy. Specific stains for elastic tissue reveal characteristic fragmentation and rarefaction of elastic fibers. We report a sporadic case of acrokeratoelastoidosis in a 13-year-old girl and review the etiology, differential diagnosis, and treatment of this disorder.

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“…DCPH is a chronic and slowly progressive rare condition, clinically characterized by bilateral and symmetrical linear and firm plaques on the medial and lateral aspects of the hands at the juncture of the palmar and dorsal skin. The main histopathological features consist of numerous dense collagen bundles haphazardly mixed with elastic fibers and an amorphous basophilic material in the reticular dermis . On the basis of the clinical and histopathological findings of the early lesions of our patient, a diagnosis of DCPH was established.…”

Section: Discussionmentioning

confidence: 85%

“…Ultraviolet radiation and chronic pressure were considered as the inciting factors . Since this original description, very few cases have been described under different names and with varied histogenetic interpretations …”

Section: Introductionmentioning

confidence: 99%

Acrolocalized variant of lichen sclerosus initially manifesting as degenerative collagenous plaques of the hands

et al. 2019

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Lichen sclerosus involving the hands is very uncommon. On the other hand, degenerative collagenous plaques of the hands is a rare condition characterized by keratotic, translucent papules in linear array, on the radial border of the hands. Histopathologically, lesions of degenerative collagenous plaques of the hands show increased collagen bundles in upper half of the dermis and dermal elastosis. We describe the clinical and histopathological progression experienced by a woman who initially presented lesions with clinical and histopathological appearance of degenerative collagenous plaques of the hands, which evolved into characteristic lichen sclerosus. We propose that some cases of the so-called degenerative collagenous plaques of the hands may represent an acrolocalized lichen sclerosus at an early stage. K E Y W O R D S acral skin, degenerative collagenous plaques of the hands, elastic tissue anomalies, lichen sclerosus

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Tender linear lesions of the fingers. Acrokeratoelastoidosis (acquired type) or degenerative collagenous plaques of the hands

Cited by 9 publications

References 0 publications

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Acrokeratoelastoidosis

Acrolocalized variant of lichen sclerosus initially manifesting as degenerative collagenous plaques of the hands

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