Telephone-Based Identification of Mild Cognitive Impairment and Dementia in a Multicultural Cohort

Cost Effective Community Based Dementia Screening: A Markov Model Simulation

“…In our study we identified new and previously undiagnosed MCI and mild dementia in 7.5% of individuals screened. This rate of detection of previously undiagnosed individuals is in good agreement with previously reported detection rates for community based screening programs which have ranged from 9 to 14% [17, 18]. The ability of community based screening programs to reach previously undiagnosed individuals with dementia has also been demonstrated by Barker et al in 2005 [19], who showed that subjects with Alzheimer's disease who were referred from a memory screening program presented with higher mean MMSE scores and shorter durations of illness than those referred by physicians or family members.…”

Cost Effective Community Based Dementia Screening: A Markov Model Simulation

“…In our study we identified new and previously undiagnosed MCI and mild dementia in 7.5% of individuals screened. This rate of detection of previously undiagnosed individuals is in good agreement with previously reported detection rates for community based screening programs which have ranged from 9 to 14% [17, 18]. The ability of community based screening programs to reach previously undiagnosed individuals with dementia has also been demonstrated by Barker et al in 2005 [19], who showed that subjects with Alzheimer's disease who were referred from a memory screening program presented with higher mean MMSE scores and shorter durations of illness than those referred by physicians or family members.…”

Screening by Telephone in the Alzheimer's Disease Anti-inflammatory Prevention Trial

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14,15], probably because of methodological differences (e.g., different cut-points). Overall, however, our observed pattern of good sensitivity for the TICS in detection of dementia but reduced sensitivity for MCI/pAD is consistent with the many reports that show the TICS is most useful in detecting unambiguous impairment.…”

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14, 15], probably because of methodological differences (e.g. different cut-points).…”

Diagnostic Accuracy of the Telephone Interview for Cognitive Status for the Detection of Dementia in Primary Care

“…One included communitydwelling older people taking part in a dementia screening program in one of the boroughs of New York City, and the other included individuals characterized by low levels of education and/or illiteracy in rural Greece. 26,27 Both studies had greater numbers of dementia cases compared to our study (9% and 10.5%, respectively, vs 3.2%) and greater sensitivity and specificity of at least 80% at optimal cutoff scores of 28 and 25, respectively. Similar optimal cutoff values, ranging from 24 to 26, were reported in other studies, rendering our cutoff score of 29 relatively high.…”

Cost Effective Community Based Dementia Screening: A Markov Model Simulation

“…In our study we identified new and previously undiagnosed MCI and mild dementia in 7.5% of individuals screened. This rate of detection of previously undiagnosed individuals is in good agreement with previously reported detection rates for community based screening programs which have ranged from 9 to 14% [17, 18]. The ability of community based screening programs to reach previously undiagnosed individuals with dementia has also been demonstrated by Barker et al in 2005 [19], who showed that subjects with Alzheimer's disease who were referred from a memory screening program presented with higher mean MMSE scores and shorter durations of illness than those referred by physicians or family members.…”

Screening by Telephone in the Alzheimer's Disease Anti-inflammatory Prevention Trial

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14,15], probably because of methodological differences (e.g., different cut-points). Overall, however, our observed pattern of good sensitivity for the TICS in detection of dementia but reduced sensitivity for MCI/pAD is consistent with the many reports that show the TICS is most useful in detecting unambiguous impairment.…”

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14, 15], probably because of methodological differences (e.g. different cut-points).…”

Diagnostic Accuracy of the Telephone Interview for Cognitive Status for the Detection of Dementia in Primary Care

“…One included communitydwelling older people taking part in a dementia screening program in one of the boroughs of New York City, and the other included individuals characterized by low levels of education and/or illiteracy in rural Greece. 26,27 Both studies had greater numbers of dementia cases compared to our study (9% and 10.5%, respectively, vs 3.2%) and greater sensitivity and specificity of at least 80% at optimal cutoff scores of 28 and 25, respectively. Similar optimal cutoff values, ranging from 24 to 26, were reported in other studies, rendering our cutoff score of 29 relatively high.…”

Cost Effective Community Based Dementia Screening: A Markov Model Simulation

“…In our study we identified new and previously undiagnosed MCI and mild dementia in 7.5% of individuals screened. This rate of detection of previously undiagnosed individuals is in good agreement with previously reported detection rates for community based screening programs which have ranged from 9 to 14% [17, 18]. The ability of community based screening programs to reach previously undiagnosed individuals with dementia has also been demonstrated by Barker et al in 2005 [19], who showed that subjects with Alzheimer's disease who were referred from a memory screening program presented with higher mean MMSE scores and shorter durations of illness than those referred by physicians or family members.…”

Screening by Telephone in the Alzheimer's Disease Anti-inflammatory Prevention Trial

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14,15], probably because of methodological differences (e.g., different cut-points). Overall, however, our observed pattern of good sensitivity for the TICS in detection of dementia but reduced sensitivity for MCI/pAD is consistent with the many reports that show the TICS is most useful in detecting unambiguous impairment.…”

“…Although it also showed excellent specificity (0.96) for MCI/pAD, its sensitivity (0.29) for the latter was very low (at least with the specified cut-off points) and, in our opinion, unacceptable. We note that somewhat better values have been reported by others [14, 15], probably because of methodological differences (e.g. different cut-points).…”

Diagnostic Accuracy of the Telephone Interview for Cognitive Status for the Detection of Dementia in Primary Care

“…One included communitydwelling older people taking part in a dementia screening program in one of the boroughs of New York City, and the other included individuals characterized by low levels of education and/or illiteracy in rural Greece. 26,27 Both studies had greater numbers of dementia cases compared to our study (9% and 10.5%, respectively, vs 3.2%) and greater sensitivity and specificity of at least 80% at optimal cutoff scores of 28 and 25, respectively. Similar optimal cutoff values, ranging from 24 to 26, were reported in other studies, rendering our cutoff score of 29 relatively high.…”