Tegretol Excipient-Induced Allergy

Are Excipients Really Inert Ingredients? A Review of Adverse Reactions to Excipients in Oral Dermatologic Medications in Canada

“…15,22,32,33 Similar reactions have also been reported from dyes other than tartrazine, such as indigotine, ponceau, sunset yellow, brilliant blue, quinolone yellow, and allura red (see Table 6). 5,6,17,22,[34][35][36][37][38][39][40][41][42][43][44][45][46][47] In general, the xanthene dyes are photosensitizers and the quinolone dyes are occasionally associated with contact sensitization. 6 The association between additives and a range of childhood behavioral problems was first suggested by Feingold 48 ; however, many well-conducted studies have since found no association between additives and hyperactivity.…”

Are Excipients Really Inert Ingredients? A Review of Adverse Reactions to Excipients in Oral Dermatologic Medications in Canada

“…15,22,32,33 Similar reactions have also been reported from dyes other than tartrazine, such as indigotine, ponceau, sunset yellow, brilliant blue, quinolone yellow, and allura red (see Table 6). 5,6,17,22,[34][35][36][37][38][39][40][41][42][43][44][45][46][47] In general, the xanthene dyes are photosensitizers and the quinolone dyes are occasionally associated with contact sensitization. 6 The association between additives and a range of childhood behavioral problems was first suggested by Feingold 48 ; however, many well-conducted studies have since found no association between additives and hyperactivity.…”

Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E‐mediated mechanism

“…Excipients also provide suitable consistency, acting as a binder, matrix, base, or diluent in pills, tablets, creams, salves, etc. An allergic reaction to a medication might be because of any component of the preparation, including dyes and excipients [5–9].…”

Are Excipients Really Inert Ingredients? A Review of Adverse Reactions to Excipients in Oral Dermatologic Medications in Canada

“…15,22,32,33 Similar reactions have also been reported from dyes other than tartrazine, such as indigotine, ponceau, sunset yellow, brilliant blue, quinolone yellow, and allura red (see Table 6). 5,6,17,22,[34][35][36][37][38][39][40][41][42][43][44][45][46][47] In general, the xanthene dyes are photosensitizers and the quinolone dyes are occasionally associated with contact sensitization. 6 The association between additives and a range of childhood behavioral problems was first suggested by Feingold 48 ; however, many well-conducted studies have since found no association between additives and hyperactivity.…”

Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E‐mediated mechanism

“…Excipients also provide suitable consistency, acting as a binder, matrix, base, or diluent in pills, tablets, creams, salves, etc. An allergic reaction to a medication might be because of any component of the preparation, including dyes and excipients [5–9].…”

Are Excipients Really Inert Ingredients? A Review of Adverse Reactions to Excipients in Oral Dermatologic Medications in Canada

“…15,22,32,33 Similar reactions have also been reported from dyes other than tartrazine, such as indigotine, ponceau, sunset yellow, brilliant blue, quinolone yellow, and allura red (see Table 6). 5,6,17,22,[34][35][36][37][38][39][40][41][42][43][44][45][46][47] In general, the xanthene dyes are photosensitizers and the quinolone dyes are occasionally associated with contact sensitization. 6 The association between additives and a range of childhood behavioral problems was first suggested by Feingold 48 ; however, many well-conducted studies have since found no association between additives and hyperactivity.…”

Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E‐mediated mechanism

“…Excipients also provide suitable consistency, acting as a binder, matrix, base, or diluent in pills, tablets, creams, salves, etc. An allergic reaction to a medication might be because of any component of the preparation, including dyes and excipients [5–9].…”