Technetium 99m as a Scanning Agent

Harper, Paul V.; Lathrop, K.A.; Jiminez, Feliciano; Fink, R.; Gottschalk, Alexander

doi:10.1148/85.1.101

Cited by 142 publications

(62 citation statements)

References 7 publications

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“…2 Previously, Sorensen had counted 99mTc in humans injected with the parent isotope 99molybdenurn (O9Mo) . 8 The decay scheme for 99M0 is given in Fig 1. 4 Many clinical uses of 99mTc have been developed, including joint scans.6-7 A technic for the visualization of diseased joints using 9 s m T~ and a scintillation (Anger) camera is the subject of this report. The data are interpreted in terms of isotope kinetics.…”

mentioning

confidence: 99%

^99mTechnetium scintiphotography in arthritis I. technic and interpretation

McCarty

Polcyn²,

Collins

et al. 1970

Arthritis & Rheumatism

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A technic for visualization of inflamed joints using intravenously injected technetium-99m as pertechnetate and an Anger (scintillation) camera for detection will be described. Contrast between inflamed and normal tissue was usually greatest in the first few minutes after isotope injection, presumably, at the time of maximal difference in concentration of 99mTc between blood and extravascular tissue. Inflamed joints with moderate to large effusions were often visualized best 1-2 hr after injection. The extensive binding of pertechnetate by plasma and joint fluid proteins found in equilibrium dialysis experiments was evoked as an explanation of this phenomenon.Technetium-99m ("9mTc) scheme for 99M0 is given in Fig 1.4 Many clinical uses of 99mTc have been developed, including joint scans.6-7 A technic for the visualization of diseased joints using 9 s m T~ and a scintillation (Anger) camera is the subject of this report. The data are interpreted in terms of isotope kinetics. MATERIALS AND METHODSSubjects. T h e optimal time of exposure was determined after scintiphotographs of the hands and wrists of 6 patients without joint disease had demonstrated a nearly uniform distribution of radioactivity (Fig 2). The "normals" were individuals receiving intravenous pertechnetate-99m for other diagnostic studies such as brain tumor localization. The hand, "wrist" and knee joints of patients with classical rheumatoid arthritis (RA) were then examined serially. Serial frontal images (ie, patella to collimator) were obtained of an inflamed knee containing a large effusion in patient E.M.Podtfonlng. Five mc lomTc, as sodium pertechnetate (NaTcO,) , were given intravenously. The

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mentioning

confidence: 99%

^99mTechnetium scintiphotography in arthritis I. technic and interpretation

McCarty

Polcyn²,

Collins

et al. 1970

Arthritis & Rheumatism

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“…The standard liver scan (or scintigram as obtained with a gamma camera) is a two-dimensional representation of the distribution of a colloidal material (sulphur colloid, usually tagged with technetium-99m) (Figure 1) (Harper et al 1965, McAfee et al 1965. The (Figure 2).…”

Section: Isotope Methodsmentioning

confidence: 99%

Diagnosis of Liver Metastases Using Ultrasound and Isotope Scanning Techniques

Cosgrove

McCready

1978

J R Soc Med

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“…Bereits mit der Einführung der 99m Tc durch Harper et al 1962(Harper et al 1965) haben diese und später Grove und DiChiro (1968) (Brands et al 1977, Hermann 1998. Jod-und Technetium-Isotope werden in den Schaltstücken und Ausführungsgängen der Kopfspeicheldrüsen aus dem Blut aufgenommen und mit dem Speichel dann sezerniert (Börner 1980, zum Winkel 1980 (Bornemann et al 1983, Schmelzeisen et al 1991.…”

Section: Die Szintigraphie In Der Diagnostik Der Speicheldrüsenunclassified

Wertigkeit der Szintigraphie und der Sonographie in der Diagnostik der Zystadenolymphome der Glandula parotis

Canbay

Knorz²,

Heimann³

et al. 2002

Laryngo-Rhino-Otol

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Hintergrund: Zystadenolymphome können 99m Technetium-Pertechnetat aufnehmen und speichern wie die Speicheldrüsen selbst. Welcher Stellenwert kommt der Speicheldrüsenszintigraphie allein oder als ergänzender Untersuchung zur Sonographie heute zu? Patienten und Methoden: Im Rahmen einer prospektiven Studie wurden 35 Patienten mit der sonographischen Diagnose bzw. Verdachtsdiagnose eines Zystadenolymphoms präoperativ szintigraphisch untersucht und mit dem Goldstandard Histologie verglichen. Ergebnisse: Zystadenolymphome konnten in 88 % (22/25) sonographisch und in 80 % (20/25) szintigraphisch als solche bestätigt werden. Schlussfolgerungen: Die Sonographie ist als ein Verfahren ohne Strahlenexposition zur Diagnostik der Zystadenolymphome ausreichend. Die Szintigraphie empfiehlt sich als ergänzendes Verfahren bei Patienten mit einer hohen Gesamtmorbidität bzw. einem höheren Operationsrisiko zur Absicherung der Diagnose. Da Zystadenolymphome ein nur äußerst geringes Entartungsrisiko haben, kann die Sonographie dann zur regelmäßigen Verlaufskontrolle genutzt werden.

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Technetium 99m as a Scanning Agent

Cited by 142 publications

References 7 publications

^99mTechnetium scintiphotography in arthritis I. technic and interpretation

^99mTechnetium scintiphotography in arthritis I. technic and interpretation

Diagnosis of Liver Metastases Using Ultrasound and Isotope Scanning Techniques

Wertigkeit der Szintigraphie und der Sonographie in der Diagnostik der Zystadenolymphome der Glandula parotis

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