Undergraduate student attrition is a major concern in higher education. It is usually explained by the impact of student attributes; however, recent developments in student success literature point to the need of exploring institutional practices that may impact a student's decision to abandon their studies. The current weight of academic quality assurance for Colombian higher education institutions (HEI) and what such measures may mean for how HEI fulfill their missions indicates the need to consider a possible relation between such quality measures and undergraduate student attrition. Using official databases from the Colombian Ministry of Education for the year 2009, this study explores through analysis of variance the relationship between attrition and three measures of academic quality: accreditation status, professional test scores required to graduate (Saber Pro Exam) and the number of research groups at HEI. The scope of the study is the Colombian Caribbean region and the sample includes 19 HEI. Study results demonstrate that the percentage of accredited undergraduate programs at HEI was the only measure of quality assurance, out of the three explored, that showed a statistically significant relationship with undergraduate student attrition rates.