2020
DOI: 10.31219/osf.io/uvtn2
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Shahan Mamoor

Abstract: Metastasis is a major problem in patients with breast cancer (1). We analyzed published microarray datasets (2, 3) to identify transcription factors whose expression changed most significantly between primary tumors in patients with breast cancer and metastatic tissues. We identified TCF4 as differentially expressed when comparing the transcriptomes of primary tumors of the breast and metastases to the liver (2). Analysis of a separate microarray dataset uncovered similar differential expression of TCF4 in …

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