Targeting noncoding RNAs to reactivate or eliminate latent HIV reservoirs
Nadejda Beliakova-Bethell
Abstract:Purpose of review
Expression of noncoding RNAs (ncRNAs) is more tissue and cell type-specific than expression of protein-coding genes. Understanding the mechanisms of action of ncRNAs and their roles in HIV replication and latency may inform targets for the latent HIV reservoir reactivation or elimination with high specificity to CD4+ T cells latently infected with HIV.
Recent findings
While the number of studies in the field of ncRNAs and HIV is limite… Show more
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