2017
DOI: 10.4158/ep171881.or
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Abstract: Objective The purpose of this study was to determine if infants with congenital hypothyroidism (CH) whose initial dose of levothyroxine (LT4) is based on thyroid gland anatomy require fewer dose adjustments in the first 6 months of life than those who were started empirically on LT4. Methods Newborns with CH who had a thyroid ultrasound performed at diagnosis were eligible for this prospective, historical case-controlled study. The daily LT4 dose prescribed was based on results on the thyroid ultra-sound as … Show more

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Cited by 7 publications
(1 citation statement)
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“…We used the recommended guidelines of 10-15 mcg/kg at diagnosis and adjustment was made according to biochemical levels. 15 , 32 Children with transient hypothyroidism were given a lower dose, which was found to be adequate enough to suppress their mildly elevated TSH. However, there was no statistical difference in the median thyroxine doses for the different 3 sub-groups.…”
Section: Introductionmentioning
confidence: 99%
“…We used the recommended guidelines of 10-15 mcg/kg at diagnosis and adjustment was made according to biochemical levels. 15 , 32 Children with transient hypothyroidism were given a lower dose, which was found to be adequate enough to suppress their mildly elevated TSH. However, there was no statistical difference in the median thyroxine doses for the different 3 sub-groups.…”
Section: Introductionmentioning
confidence: 99%