Talc deposition in skin and tissues surrounding silicone gel-containing prosthetic devices

Remission of Sarcoidosis following Removal of Silicone Gel Breast Implants

“…A recent histologic study on im plant capsule tissues found biréfringent crystals containing magnesium and silicon, presumed to be talc introduced on gloves or on the implants [7], Talc is a magnesium silicate and a known cause of granulomatous and fibrous inflamma tion [8]. However, the crystals seen in our patient are smaller than talc crystals if found contaminating a surgical field.…”

Foreign body post‐varicella granulomas due to talc

“…referring to mammary implants. 6 On occasions, foreign body granulomas are produced by the use of cosmetic or hygiene products, such as those described in axilla due to talc contained in some deodorants. 8 Tye et al .…”

“…9,10,13 Through polarized light examination, the magnesium silicate crystals present a typical morphology in the shape of 'spicules', which reveal white birefringence. 6,9 Using electron microscopy, highly electrodense laminar structures can be visualized inside the cytoplasm of histiocytes and epithelioid cells. This has also been described in other phagocytic cells.…”

“…Cutaneous and/or subcutaneous foreign body granulomas caused by talc (magnesium silicate) have been reported for different causes and in diverse circumstances. Thus there are cases described such as granulomas in surgical wounds due to the talc contained in some gloves as a lubricant, 6 or following topical treatment of a wound with antiseptic powder 7 . Some authors have suggested that contamination of surgical implants with talc can induce granuloma formation, such as in the article published by Kasper et al .…”

“…Some authors have suggested that contamination of surgical implants with talc can induce granuloma formation, such as in the article published by Kasper et al . referring to mammary implants 6 …”