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Cited by 4 publications
(9 citation statements)
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References 7 publications
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“…Since our patients were at different ages, it is essential to consider this. Chronic inflammation, which comprises the endothelium, is associated with HIV infection [ 26 ] and the natural aging process without HIV infection [ 27 ]. However, endothelial dysfunction occurs earlier and is accelerated in HIV-positive subjects [ 28 ].…”
Section: Discussionmentioning
confidence: 99%
“…Since our patients were at different ages, it is essential to consider this. Chronic inflammation, which comprises the endothelium, is associated with HIV infection [ 26 ] and the natural aging process without HIV infection [ 27 ]. However, endothelial dysfunction occurs earlier and is accelerated in HIV-positive subjects [ 28 ].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, short-term HIF overexpression has beneficial effects on the heart, and long-term HIF stabilization is associated with cardiomyopathy [52]. Recent emerging data reveal crosstalk between HIF-1α and cellular senescence-associated cardiovascular aging (Table 1) [3,29,[52][53][54].…”
Section: Hypoxia-inducible Factorsmentioning
confidence: 99%
“…Despite the complex relationship between HIF and aging, Kaluz et al recently noted that several age-associated maladies involve the disarray or activation of the hypoxia response mechanism, mainly the HIF transcriptional factor [3]. In part, this phenomenon could be related to evidence for the overactivation of hypoxia responses to a modestly slow aging life, associated with beneficial stress responses in various animal studies.…”
Section: The Physio-pathological Role Of Hif In Agingmentioning
confidence: 99%
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