2018
DOI: 10.1021/acsbiomaterials.7b00689
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Abstract: Nanotechnology has acquired an immense recognition in cancer theranostics. Considerable progress has been made in the development of targeted drug delivery system for potent delivery of anticancer drugs to tumor-specific sites. Recently, multifunctional nanomaterials have been explored and used as nanovehicles to carry drug molecules with enhanced therapeutic efficacy. In this present work, graphene oxide quantum dot (GOQD) was conjugated with folic acid functionalized chitosan (FA-CH) to develop a nanocargo (… Show more

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Cited by 45 publications
(31 citation statements)
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“…No differences were observed between the two different protocols. Therefore, by washing GQDs before Dox administration, we could exclude the hypotheses of GQDs’ and Dox’s extracellular interaction [ 43 ]. When pretreated with NH 2 -GQDs, no changes in cell viability were measured for all the cell lines investigated ( Figure 4 A,B).…”
Section: Resultsmentioning
confidence: 99%
“…No differences were observed between the two different protocols. Therefore, by washing GQDs before Dox administration, we could exclude the hypotheses of GQDs’ and Dox’s extracellular interaction [ 43 ]. When pretreated with NH 2 -GQDs, no changes in cell viability were measured for all the cell lines investigated ( Figure 4 A,B).…”
Section: Resultsmentioning
confidence: 99%
“…A large amount of research has been done to optimize GQDs'-associated drug delivery systems [110][111][112]. Iannazzo and colleagues designed a new biocompatible and cell traceable drug delivery system, capable of releasing the therapeutic agent doxorubicin to cancer cells in a selective manner [113].…”
Section: Gqds As Drug Delivery Systemsmentioning
confidence: 99%
“…This material exhibits a vast number of properties including long time luminescence stability, ability to be well-dispersed in aqueous media, biocompatibility, and low toxicity [8,9], making it an important and promising material for biomedical applications [10]. Due to their properties, graphene oxide quantum dots (GOQDs) are excellent probes for high-contrast bioimaging and biosensing applications, [5,11,12] e.g., biosensors [13,14], and can be used in anticancer therapies [15,16]. GO allows obtaining a vast diversity of structures having specific/controllable biological properties [8,17].…”
Section: Introductionmentioning
confidence: 99%