1993
DOI: 10.1001/archderm.129.3.379b
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Systemic sensitization to ethanol by transdermal estrogen patches

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Cited by 9 publications
(3 citation statements)
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“…However, contact allergy to alcohols of the skin seems to be rare and has mainly been reported sporadically as case reports to medical alcohol swabs 42–44 or to ethanol in oestrogen patches 45,46 . Cases of contact urticaria with anaphylactoid reactions have also been described 47,48 . As commercially available alcohols are not usually pure, impurities and contaminants could be responsible for positive cutaneous reactions.…”
Section: Discussionmentioning
confidence: 99%
“…However, contact allergy to alcohols of the skin seems to be rare and has mainly been reported sporadically as case reports to medical alcohol swabs 42–44 or to ethanol in oestrogen patches 45,46 . Cases of contact urticaria with anaphylactoid reactions have also been described 47,48 . As commercially available alcohols are not usually pure, impurities and contaminants could be responsible for positive cutaneous reactions.…”
Section: Discussionmentioning
confidence: 99%
“…caused by eth. can be induced experimentally (7), as well as from repeated occupational exposures to disinfectants or transdermal patches (4,8).…”
mentioning
confidence: 99%
“…Several cases of allergic contact reactions from estradiol transdermal therapeutic systems (TTS) have been published, mostly due to the delivery system (1) or to a component of the gel (2), namely hydroxypropyl cellulose (3) or ethanol (4,5). Estradiol was the probable cause in half a dozen cases (1,6,7), but confirmed only in 2 where patch testing with estradiol was performed (8,9).…”
mentioning
confidence: 99%