Systemic Effects Produced by Echothiophate Iodide in Treatment of Glaucoma

Local Administration of 1% Ubretid in the Handling of Glaucoma, Myasthenia Gravis and Esotropia

“…Side reactions were recognized in almost all cases, but they were only complained in the initial administra tion and were alleviated following the continuous use of the medica tion. The systemic side reactions were not obtained in the present study [14][15][16][17][18][19][20]. Though the duration of the observation is relatively shorter in the present study, the drug seemed to be milder in causing side reactions than in other similar drugs.…”

Local Administration of 1% Ubretid in the Handling of Glaucoma, Myasthenia Gravis and Esotropia

“…Side reactions were recognized in almost all cases, but they were only complained in the initial administra tion and were alleviated following the continuous use of the medica tion. The systemic side reactions were not obtained in the present study [14][15][16][17][18][19][20]. Though the duration of the observation is relatively shorter in the present study, the drug seemed to be milder in causing side reactions than in other similar drugs.…”

Glaucoma, Miotic Therapy and Cataract

“…It has been discussed (de Roetth 1966 a) if the cataract seen after treatment with Phospholine Iodide may be associated with the systemic effects of the drug, for instance the lowered level of blood cholinesterase reported by many investigators (Leopold et al 1959;Klendskoj and Olmstead 1963;Humphreys and Holmes 1963;Spiers and Juul 1964;de Roetth et al 1965). However, in the unilateral Phospholine Iodide-treated cases included in the present study ASCV were found only in the eye treated with this drug.…”

TOPICALLY ADMINISTERED DEMEKASTIGMINE BROMIDE AS A CHOLINESTERASE INHIBITOR1

“…The inhibition of the AChE of erythrocytes and of the non-specific cholinesterase (ns. ChE) of plasma caused by cholinesterase inhibitors such as phospholine iodide, demekastigmine bromide and DFP is demonstrable after a few instillations into the eyes (Leopold et al, 1959, Humpreys and Holmes, 1963, and Klenshoj and Olmsted, 1963.…”

Local Administration of 1% Ubretid in the Handling of Glaucoma, Myasthenia Gravis and Esotropia

“…Side reactions were recognized in almost all cases, but they were only complained in the initial administra tion and were alleviated following the continuous use of the medica tion. The systemic side reactions were not obtained in the present study [14][15][16][17][18][19][20]. Though the duration of the observation is relatively shorter in the present study, the drug seemed to be milder in causing side reactions than in other similar drugs.…”

Glaucoma, Miotic Therapy and Cataract

“…It has been discussed (de Roetth 1966 a) if the cataract seen after treatment with Phospholine Iodide may be associated with the systemic effects of the drug, for instance the lowered level of blood cholinesterase reported by many investigators (Leopold et al 1959;Klendskoj and Olmstead 1963;Humphreys and Holmes 1963;Spiers and Juul 1964;de Roetth et al 1965). However, in the unilateral Phospholine Iodide-treated cases included in the present study ASCV were found only in the eye treated with this drug.…”

TOPICALLY ADMINISTERED DEMEKASTIGMINE BROMIDE AS A CHOLINESTERASE INHIBITOR1

“…The inhibition of the AChE of erythrocytes and of the non-specific cholinesterase (ns. ChE) of plasma caused by cholinesterase inhibitors such as phospholine iodide, demekastigmine bromide and DFP is demonstrable after a few instillations into the eyes (Leopold et al, 1959, Humpreys and Holmes, 1963, and Klenshoj and Olmsted, 1963.…”

Local Administration of 1% Ubretid in the Handling of Glaucoma, Myasthenia Gravis and Esotropia

“…Side reactions were recognized in almost all cases, but they were only complained in the initial administra tion and were alleviated following the continuous use of the medica tion. The systemic side reactions were not obtained in the present study [14][15][16][17][18][19][20]. Though the duration of the observation is relatively shorter in the present study, the drug seemed to be milder in causing side reactions than in other similar drugs.…”

Glaucoma, Miotic Therapy and Cataract

“…It has been discussed (de Roetth 1966 a) if the cataract seen after treatment with Phospholine Iodide may be associated with the systemic effects of the drug, for instance the lowered level of blood cholinesterase reported by many investigators (Leopold et al 1959;Klendskoj and Olmstead 1963;Humphreys and Holmes 1963;Spiers and Juul 1964;de Roetth et al 1965). However, in the unilateral Phospholine Iodide-treated cases included in the present study ASCV were found only in the eye treated with this drug.…”

TOPICALLY ADMINISTERED DEMEKASTIGMINE BROMIDE AS A CHOLINESTERASE INHIBITOR1

“…The inhibition of the AChE of erythrocytes and of the non-specific cholinesterase (ns. ChE) of plasma caused by cholinesterase inhibitors such as phospholine iodide, demekastigmine bromide and DFP is demonstrable after a few instillations into the eyes (Leopold et al, 1959, Humpreys and Holmes, 1963, and Klenshoj and Olmsted, 1963.…”