Systematic review on factors associated with medication non-adherence in Parkinson's disease

Daley, David James; Myint, Phyo Kyaw; Gray, Richard; Deane, Katherine

doi:10.1016/j.parkreldis.2012.09.004

Cited by 101 publications

(119 citation statements)

References 33 publications

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“…However, despite promising findings in case studies (Moitra et al, 2011;Nes et al, 2012), no comprehensive trials of this were evident in the present review. This is a missed opportunity since non-adherence to medication is a major public health problem, with an estimated 30-50% of medication not taken as recommended (Horne et al, 2005) and non-adherence being a behaviour(s) with a range of cognitive-behavioural correlates (Daley, Myint, Gray , & Deane, 2012;Horne & Weinman, 1999;. Therefore, ACT may be applicable (Graham et al, 2012).…”

Section: A Summary Of the Use Of Act In Long-term Conditionsmentioning

confidence: 99%

A systematic review of the use of Acceptance and Commitment Therapy (ACT) in chronic disease and long-term conditions

Graham

Gouick

Krahé

et al. 2016

Clinical Psychology Review

356

280

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Many have proposed that Acceptance and Commitment Therapy (ACT) may be particularly effective for improving outcomes in chronic disease/long-term conditions, and ACT techniques are now being used clinically. However, reviews of ACT in this context are lacking, and the state of evidence is unclear. This systematic review aimed to: collate all ACT interventions with chronic disease/long-term conditions, evaluate their quality, and comment on efficacy. Ovid MEDLINE, EMBASE and Psych Info were searched. Studies with solely mental health or chronic pain populations were excluded. Study quality was then rated, with a proportion re-rated by a second researcher. Eighteen studies were included: eight were randomised controlled trials (RCTs), four used pre-post designs, and six were case studies. A broad range of applications were observed (e.g. improving quality of life and symptom control, reducing distress) across many diseases/conditions (e.g. HIV, cancer, epilepsy).However, study quality was generally low, and many interventions were of low intensity. The small number of RCTs per application and lower study quality emphasise that ACT is not yet a well-established intervention for chronic disease/long-term conditions. However, there was some promising data supporting certain applications: parenting of children with long-term conditions, seizure-control in epilepsy, psychological flexibility, and possibly disease selfmanagement.

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Section: A Summary Of the Use Of Act In Long-term Conditionsmentioning

confidence: 99%

A systematic review of the use of Acceptance and Commitment Therapy (ACT) in chronic disease and long-term conditions

Graham

Gouick

Krahé

et al. 2016

Clinical Psychology Review

356

280

View full text Add to dashboard Cite

show abstract

“…Use of the apomorphine pump can also simplify the treatment of PD by providing a convenient alternative to complex oral dosing regimens which are known to impact on adherence to therapy [32,33]. It can also potentially minimize drugedrug interactions that might arise from taking multiple oral medications [34], or may be used temporarily when oral intake or absorption is limited for surgical or other reasons.…”

Section: Suitable Candidates For Continuous Apomorphine Infusion (Pump)mentioning

confidence: 99%

Expert Consensus Group report on the use of apomorphine in the treatment of Parkinson's disease – Clinical practice recommendations

Trenkwalder

Chaudhuri

Ruiz

et al. 2015

Parkinsonism & Related Disorders

141

109

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Extensive published evidence supports the use of subcutaneously-administered apomorphine as an effective therapy for Parkinson's disease (PD) but to date no consensus recommendations have been available to guide healthcare professionals in the optimal application of apomorphine therapy in clinical practice. This document outlines best-practice recommendations for selecting appropriate candidates for apomorphine intermittent injection (the pen-injection formulation) or apomorphine continuous infusion (the pump formulation), for initiating patients onto therapy and for managing their ongoing treatment. Apomorphine is a suitable therapeutic option for PD patients who experience troublesome 'off' periods despite optimized treatment with oral PD medications. Due to its speed of onset, apomorphine injection is particularly suited to those patients requiring rapid, reliable relief of both unpredictable and predictable 'off' periods, those who require reliable and fast relief when anticipating an 'off', those with levodopa absorption or gastric emptying problems resulting in delayed or failed 'on', or for rapid relief of early morning dystonia or akinesia. Apomorphine infusion(1) is suited for patients whose 'off' periods can no longer be adequately controlled by standard oral PD treatment or for those in whom rescue doses of apomorphine injection are effective but either needed too frequently (more than 4-6 times per day), or are associated with increasing dyskinesia. In addition to treating motor fluctuations, there is evidence that apomorphine infusion may be effective for the management of specific non-motor symptoms of PD associated with 'off' periods. Apomorphine infusion is less invasive than other non-oral treatment options for advancing disease, intrajejunal levodopa infusion and deep-brain stimulation.

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“…Through a systematic review, Daley et al (2012) found several demographic factors associated with nonadherence, including younger age and low income. 24 Grosset et al (2005) showed that increased age was associated with better overall adherence, 25 which is consistent with our findings that patients with higher adherence were older than patients with lower adherence. Of note, however, is that the age difference between the high and low adherent groups in our study was only 1 year, although it was statistically significant.…”

Section: ■■ Discussionmentioning

confidence: 99%

Geospatial Analysis of Statin Adherence Using Pharmacy Claims Data in the State of Michigan

Erickson¹,

Lin²

2014

JMCP

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BACKGROUND: Research has demonstrated that variation in availability and utilization of health care resources exist on a range of scales, from regions of the United States, hospital referral regions, ZIP codes, and census tracts. Limited research using spatial analyses has found that variation in medication adherence exists across census tracts. Using spatial analysis, researchers may be able to effectively analyze geographically dispersed data to determine whether factors such as sociodemographics, local shared beliefs and attitudes, barriers to access such as availability of prescribers or pharmacies, or others are associated with variations in medication adherence in a defined geographic area.

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Systematic review on factors associated with medication non-adherence in Parkinson's disease

Cited by 101 publications

References 33 publications

A systematic review of the use of Acceptance and Commitment Therapy (ACT) in chronic disease and long-term conditions

A systematic review of the use of Acceptance and Commitment Therapy (ACT) in chronic disease and long-term conditions

Expert Consensus Group report on the use of apomorphine in the treatment of Parkinson's disease – Clinical practice recommendations

Geospatial Analysis of Statin Adherence Using Pharmacy Claims Data in the State of Michigan

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