2021
DOI: 10.1200/go.21.00079
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Abstract: PURPOSE Cancer occurrence is increasing in Africa, although research has lagged. The objective of this review was to analyze cancer research outputs from Africa, with a particular focus on Zambia. METHODS We searched PubMed for published cancer-related articles from African countries. All articles reporting on cancer in Africa were considered. We conducted analyses to explore correlations between cancer research output and total population, gross domestic product, and new cancer cases recorded in 2020. For Zam… Show more

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Cited by 8 publications
(5 citation statements)
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References 17 publications
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“…In a similar population to ours, whole-exome sequencing and RNA transcriptomic analysis of 59 Malawian OC patients did not find any signatures of tobacco smoking [26], while mutational signatures for tobacco were reported in a study that included samples from 8 countries, including East Africa [13]. Africa has had a relatively low cancer research output, with most of its publications coming out of South Africa and Egypt [27]. With limited outputs from countries most heavily affected by OC, risk factors that could be affecting African populations have not been thoroughly investigated.…”
Section: Discussionsupporting
confidence: 66%
“…In a similar population to ours, whole-exome sequencing and RNA transcriptomic analysis of 59 Malawian OC patients did not find any signatures of tobacco smoking [26], while mutational signatures for tobacco were reported in a study that included samples from 8 countries, including East Africa [13]. Africa has had a relatively low cancer research output, with most of its publications coming out of South Africa and Egypt [27]. With limited outputs from countries most heavily affected by OC, risk factors that could be affecting African populations have not been thoroughly investigated.…”
Section: Discussionsupporting
confidence: 66%
“…While there has been a welcome increase in cancer research over the last decade, this is unevenly distributed. Just 13 of 54 African countries were responsible for around 90% of total cancer research, with two countries contributing two-thirds of the entire continent’s cancer (and NCD) research, namely Egypt and South Africa 23 24. This critical finding speaks to the need for each country to develop a strategic plan to build cancer research as an integral part of their National Cancer Control Plans.…”
Section: Discussionmentioning
confidence: 99%
“…Globally, cancer is a critical public health challenge because it is a predominant cause of death and presents a consistent and incrementally growing incidence rate (Siegel et al, 2020;Sung et al, 2021). The rise in cancer incidences in Africa are described as unprecedented and expected to double by 2040 (Kayamba et al, 2021). In the African context, this overwhelming increase in the need for cancer care exacerbates QWL concerns in an already overburdened oncology system (Wentzel et al, 2019).…”
Section: Introductionmentioning
confidence: 99%