System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

Vyslotska, L. V.; Gutyj, B. V.; Kozenko, O. V.; Khalak, V. I.; Chornyi, V.; Martyshuk, T. V.; Krempa, N. Yu.; Vozna, O. Ye.; Todoriuk, V. B.

doi:10.32718/nvlvet10402

Cited by 9 publications

(9 citation statements)

References 12 publications

(12 reference statements)

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“…The obtained results indicate the inhibition of erythrocytopоesis with a simultaneous increase in the size of erythrocytes (macrocytosis) and their hemoglobin content due to digestive tract digestion and vitamin B12 absorption from the intestine. The established RDW norm of heterogeneity of red blood cells allowed minor deviations (7.9 %), which could be due to the redistribution of white blood cells, since according to Vyslotska et al (2021), in the period of stress, neutrophilia and eosinopenia are observed. However, the obtained RDW erythrocyte's anisotropy coefficient affected the ability to transport oxygen and carbon dioxide.…”

Section: Tablementioning

confidence: 99%

Erythron and protein system in piglets blood under stress influence

Kovalchuk

Slepokura

Kolomiiets

et al. 2022

Ukr. Jour. of Vet. and Agr. Sci.

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The article presents the results of research on the development of adaptive syndrome in the system of erythron and protein of piglets at the effects of weaning stress. After one (anesthetic stage) and seven days (beginning of G.Selle's resistance stage), after the echoing, the adaptation of the erythron system was shown by a decrease in the number of red blood cells on the contrary of increasing the mean corpuscular volume and hemoglobin indicating the inhibition of erythrocytosis with simultaneous macrocytosis, and a decrease in mean Corpuscular hemoglobin concentration for 14.0–13.0 % that indicated hypochromia. In these stressful periods, the catabolism of protein substrates was discovered, the redistribution of albumins between blood and tissues in the form of a decrease in the total protein content by 6.1–7.1 % due to albumin by 14.8–10.0 %, and the deficit of the humoral link of the immune response due to reduction of γ-globulins by 29.9–18.7 %. In the later stages of the resistance stage (after 20 and 60 days after weaning), there was a stabilization of erythrocytic indices and the development of anisocytosis in the form of an increase in red cell distribution width by 19.0 %, with a simultaneous decrease of 6.1 % of the total protein content, redistribution of its fractions in the side of the growth of γ-globulins by 18.4 %. A practical, prolonged way of preventing disorders in the erythron and protein of extramarital piglets was feeding the additive “Biovir”, which stimulated the intensity of oxidative-reducing processes and the exchange of proteins.

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Section: Tablementioning

confidence: 99%

Erythron and protein system in piglets blood under stress influence

Kovalchuk

Slepokura

Kolomiiets

et al. 2022

Ukr. Jour. of Vet. and Agr. Sci.

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“…Важливу роль в підтримці прооксидантноантиоксидантного потенціалу відіграє еритроцитарний гомеостаз, що, крім того, забезпечує функціонування системи метаболізму Оксигену Martyshuk et al, 2021;Vyslotska et al, 2021). Знижена кількість еритроцитів у крові кнурів дослідної групи головним чином позначалася на їхніх антирадикальних й антигіпоксичних здатностях (рис.…”

Section: рис 2 основні показники гоместазу кнурівunclassified

Biochemical and mineral status of the body of infertile boars with hypovitaminosis A

Naumenko¹,

Miroshnikova²,

Викулина³

2023

SMLNUVMB

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A leading role in the occurrence of infertility in male domestic animals is played by nutritional deficiency factors, in particular vitamin A deficiency, which contributes to the development of morphological and functional changes in the reproductive system. The aim of the work was to determine the effect of vitamin A (carotene) deficiency on the biochemical and mineral status of infertile boars, in particular, to establish changes in the main biochemical markers and assess the state of the antioxidant defence system and indicators of mineral homeostasis (Calcium, Phosphorus, Zinc, Copper, Manganese and Cobalt). In the experimental group of animals, a probably low level of vitamin A was noted (by 54.2 % lower than the control group, P ˂ 0.001) due to a significant increase in the content of thiobarbiturate acid-reactive compounds (by 2.32 times, P ˂ 0.001) and a decrease in the activity of catalase and superoxide dismutase (by 47.3 % and 28.8 %, respectively, P ˂ 0.001). A decrease in haemoglobin concentration by 14.3 % (Р ˂ 0.001), total protein by 11.6 % (Р ˂ 0.01), the number of erythrocytes by 9.3 % (Р ˂ 0.01) and acid capacity by 9.1 % (Р ˂ 0.05). These results demonstrate a general decrease in metabolic processes in the body of infertile boars with vitamin A deficiency. The reduced number of erythrocytes in the blood of boars of the experimental group was mainly due to antiradical and antihypoxic abilities. It should be noted that catalase activity and the content of reduced glutathione in erythrocytes were probably lower than the control indicators by 53.1 % and 16.3 % (Р ˂ 0.001), respectively. In addition, taking into account the reduced indicators of haemoglobin content and the number of erythrocytes, a negative dynamics of oxygen metabolism was established. This is also confirmed by a probable increase in the content of 2,3-diphosphoglycerate in erythrocytes (by 67.5 %, Р ˂ 0.001). Also, in boars of the experimental group, the content of Calcium was lower by 25.0 % (Р ˂ 0.001) than the control indicators, and the content of Phosphorus decreased by 12.6 % (Р ˂ 0.05). Similar changes were observed in the levels of Zinc and Copper (indicators were lower than the control by 52.0 % and 28.0 %, respectively, Р ˂ 0.001). Note that the Manganese content in the blood of experimental boars was reduced by 20.9 % (Р ˂ 0.05), while the Cobalt level was lower by 16.1 % (Р ˂ 0.05). The obtained results showed a significant effect of A-vitamin deficiency on the general antioxidant activity and mineral homeostasis in barren boars.

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“…Дослідження багатьох як вітчизняних, так і закордонних науковців спрямовані на стимулювання природних захисних властивостей організму тварин (Krempa & Kozenko, 2018;Martyshuk et al, 2020;Taşlıdere et al, 2022;Saifi et al, 2022;Askin et al, 2022), здатних зменшити негативний вплив технологічного процесу та зміцнювати імунні функції організму. Значне зацікавлення дослідники виявляють до застосування імуностимуляторів різного походження, до яких належать не лише фармакологічні форми, а й біологічно активні кормові добавки, пробіотики (Kovalenko & Yamtsul, 2012;Vyslotska et al, 2021;Kozenko et al, 2021).…”

Section: вступunclassified

Dynamics of morphological and biochemical indicators of blood of young pigs using Globigen® Pig Doser and Globigen ® Jump Start with different methods of their keeping

et al. 2022

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The article deals with the influence of Globigen® Pig Doser and Globigen® Jump Start products, which contain specific Ig Y, which is characterized by pronounced immunostimulating properties. A comprehensive analysis of the use and influence of these agents on the morphological and biochemical indicators of the blood of young pigs under conditions of intensive technologies under different methods of cultivation in different periods of their growth and development – 30, 60, and 120 days – was carried out. It was set that the use of the proposed means had a prolonged positive effect, which concerning hematological indicators, mainly appeared by an increase in the number of erythrocytes and the concentration of hemoglobin in the blood of experimental groups of animals of both farms of all age periods. It is worth noting that in the farm with single-phase breeding of pigs (FE PE “Glynyany Agro”) under the influence of Globigen®Pig Doser, the number of erythrocytes in the blood of animals was increased and, corresponding to the physiological norm, fluctuated between 7.09 and 7.43 T/l, and the concentration of hemoglobin, having reached the maximum value, in the blood of all experimental groups of animals was 108.62–112.77 g/l. In the farm, which practices three-phase pig breeding (“Meat Resources” Ltd.), under the influence of Globigen® Pig Doser, a pronounced effect has appeared in animals 60 and 120 days old; the number of erythrocytes in their blood was increased to 7.46–7.69 T/l, and under the influence of Globigen® Jump Start, a tendency to a gradual increase in hemoglobin concentration was observed, which stopped at 99.28 g/l in 120-day-old piglets. Evaluating the level of protein metabolism in animals under the influence of Globigen® Pig Doser and Globigen® Jump Start, a tendency to increase the total protein content, compared to the control, in the blood of animals in all age periods in both farms was set. It was noted that under the action of Globigen®Jump Start, the total protein content in the blood of 120-day-old piglets from a farm with single-phase farming (FE PE “Glynyany Agro”) was 76.38 g/l, and in a farm with three-phase farming (Ltd. “Meat resources”) 75.08 g/l. In addition, it was set that the normalization of the ratio of protein fractions, in particular, the use of Globigen® Pig Doser and Globigen® Jump Start, increased the synthesis of albumin and normalized gamma-globulin to the level of the physiological norm. The “Glynyany Agro” FE found a more pronounced effect with single-phase piglet rearing. It was concluded that Globigen® Pig Doser and Globigen® Jump Start positively influence maintaining body homeostasis.

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System of antioxidant protection of the body of piglets under the action of feed additive “Sylimevit”

Cited by 9 publications

References 12 publications

Erythron and protein system in piglets blood under stress influence

Erythron and protein system in piglets blood under stress influence

Biochemical and mineral status of the body of infertile boars with hypovitaminosis A

Dynamics of morphological and biochemical indicators of blood of young pigs using Globigen® Pig Doser and Globigen ® Jump Start with different methods of their keeping

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