volume 27, issue 4, P705-722 2013
DOI: 10.1016/j.idc.2013.08.005
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Stephanie E. Cohen, Jeffrey D. Klausner, Joseph Engelman, Susan Philip

Abstract: Syphilis is a complex, systemic disease caused by the spirochete Treponema pallidum. Syphilis is most commonly transmitted sexually or congenitally and can involve nearly every organ system. Its clinical progression involves several well-characterized stages: an incubation period, a primary stage, a secondary stage, a latent stage, and a late or tertiary stage. Syphilis during pregnancy is a leading cause of perinatal mortality in sub-Saharan Africa and can cause spontaneous abortion, stillbirth, prematurity, …

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