Synthesis, structural, electrochemical and corrosion inhibition properties of two new ferrocene Schiff bases derived from hydrazides

Gupta, Shraddha; Mourya, Punita; Singh, Manjeet; Singh, Vinod P.

doi:10.1016/j.jorganchem.2014.05.038

Cited by 49 publications

(26 citation statements)

References 40 publications

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“… Also the Fe‐C bond of the Schiff base was observed at 462 cm ‐1 . 1 H‐NMR spectrum of Schiff base ligand showed multiplet signals in the region of 4.22‐4.76 ppm, which attributed to the ferrocene protons . Also proton signals were observed as multiplet peak in aromatic region around 6.00‐7.39 ppm.…”

Section: Resultsmentioning

confidence: 96%

Metal complexes of novel Schiff base derived from iron sandwiched organometallic and 4‐nitro‐1,2‐phenylenediamine: Synthesis, characterization, DFT studies, antimicrobial activities and molecular docking

Mahmoud

Deghadi

2018

Applied Organom Chemis

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The condensation of 2-acetylferrocene with 4-nitro-1,2-phenylenediamine in a 1:1 molar ratio, resulting in formation of a novel bi-dentate organometallic Schiff base ligand (L), (2-(1-((2-amino-5-nitrophenyl)imino)ethyl)cyclopenta-2,4-dien-1-yl)(cyclopenta-2,4-dien-1-yl)iron. Also, its Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes have been synthesized. The stoichiometric ratios of the prepared compounds were estimated using elemental analysis (C, H, N, M), molar conductivity, FT-IR, UV-Vis, 1 H-NMR, SEM and mass spectral analysis. Furthermore, their TG and DTG properties were studied. The geometrical structure of the complexes was found to be octahedral. From spectral analysis, the Schiff base coordinated to metal ions through the azomethine and amine groups. DFT-based molecular orbital energy calculations of the synthesized ligand have been studied, in which the ligand was theoretically optimized.The Schiff base and its metal complexes have been screened for their antimicrobial activities against different bacterial and fungal species by using disc diffusion method. The anticancer activities of the ligand and its metal complexes have also been studied towards breast cancer (MCF-7) and human normal melanocytes (HFB-4) cell lines. Molecular docking was also used to identify the interaction between the Schiff base ligand and its Cd(II) complex with the active site of the receptors of breast cancer mutant oxidoreductase (PDB ID: 3HB5), crystal structure of Staphylococcus aureus (PDB ID: 3Q8U) and yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans (PDB ID:5JPE).

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Section: Resultsmentioning

confidence: 96%

Metal complexes of novel Schiff base derived from iron sandwiched organometallic and 4‐nitro‐1,2‐phenylenediamine: Synthesis, characterization, DFT studies, antimicrobial activities and molecular docking

Mahmoud

Deghadi

2018

Applied Organom Chemis

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“…5 These properties make them suitable candidates for various applications in materials science including the design of new catalytic materials and organic synthesis, redox sensors for molecular recognition, electroactive and aerospace materials. 6,7 Schiff bases having a ferrocene moiety have drawn substantial consideration due to their superior anticancer and free-radical scavenging properties. 8 Other industrial applications of ferrocene derivatives include their use as additives for heating oil to diminish smut formation, protective coatings for satellites and rockets, and UV absorbers.…”

Section: Introductionmentioning

confidence: 99%

Biferrocenyl Schiff bases as efficient corrosion inhibitors for an aluminium alloy in HCl solution: a combined experimental and theoretical study

et al. 2020

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“…Due to the ease of functionalization of ferrocene, its derivatives have found many applications in medicinal chemistry, such as antitumor [4][5][6], anti-HIV [7,8], antimalarial [9], antifungal [10], cytotoxic compounds [11,12], and for deoxyribonucleic acid (DNA) cleavage [13,14].…”

Section: Introductionmentioning

confidence: 99%

Computational Molecular Docking, Voltammetric and Spectroscopic DNA Interaction Studies of 9N-(Ferrocenylmethyl)adenine

Lanez¹,

Bechki²,

Lanez³

2019

ChChT

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The binding free energy of 9 N-(ferrocenylmethyl)adenine (FMA) with double-stranded deoxyribonucleic acid (DNA) was measured in solution using cyclic voltammetry and electronic spectroscopy (UV-Vis) techniques under similar conditions. The obtained results were confirmed by computational molecular docking. The docking studies yield good approximation with experimental data and showed that the ligand FMA is placed in the minor groove of DNA.

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Synthesis, structural, electrochemical and corrosion inhibition properties of two new ferrocene Schiff bases derived from hydrazides

Cited by 49 publications

References 40 publications

Metal complexes of novel Schiff base derived from iron sandwiched organometallic and 4‐nitro‐1,2‐phenylenediamine: Synthesis, characterization, DFT studies, antimicrobial activities and molecular docking

Metal complexes of novel Schiff base derived from iron sandwiched organometallic and 4‐nitro‐1,2‐phenylenediamine: Synthesis, characterization, DFT studies, antimicrobial activities and molecular docking

Biferrocenyl Schiff bases as efficient corrosion inhibitors for an aluminium alloy in HCl solution: a combined experimental and theoretical study

Computational Molecular Docking, Voltammetric and Spectroscopic DNA Interaction Studies of 9N-(Ferrocenylmethyl)adenine

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