Synthesis of Supramolecular Nanotubes

Abstract

In the last few years, interest on nanotubes have induced the development of programs for the preparation of noncovalently bonded self‐organizing nanotubes from a variety of different methods, in most cases inspired by nature. These strategies include helically folded linear species, hollow bundles of rod‐like units, rolled‐up sheets, helically juxtapositioned truncated wedges, and stacked rings.

Induced α,γ‐cyclic peptide rotodimer recognition by nucleobase scaffolds

“…Stacking of flat‐shaped CPs represents one the most valuable methods for the preparation of nanotubes due to the precise control of nanotube properties . One of the challenges in the field of CP nanotubes is to develop an input switcher to tune the nanotube surface properties through the control of the type of cross‐strand interactions involved in the stabilization of the staked components . The appropriate design of CP subunit allows the control of the nanotube properties for specific applications.…”

Recent advances in controlling the internal and external properties of self-assembling cyclic peptide nanotubes and dimers

“…Nanometre-scale tube-like structures (nanotubes) are amongst the most pursued nanocomponents based on the variety of proposed applications. [1][2][3][4][5][6][7] Most of the anticipated functions, which are inspired by the role of tubular structures in Nature, might be implemented in fields such as optics, electronics, catalysis, separation technologies, medicinal chemistry, molecular transport and sensing amongst others. The successful development of the most relevant applications depends on the ability to prepare these materials with a uniform internal diameter and to have precise control over the length.…”

“…3 Following the previously cited strategies, different biomolecules (DNA, lipids, carbohydrates or peptides) have been used in the preparation of nanotubes. 6 Of these molecules, peptides are the most useful buildings blocks because they offer the possibility of preparing materials with defined properties depending on the selected amino acids and their disposition in the final supramolecular assembly. 18 For this reason, self-assembling cyclic peptide nanotubes (SCPNs) are amongst the most widely pursued nanostructures.…”

DFT investigation and molecular dynamic simulation on the selective complexation of cis-cyclic nanopeptides with alkaline earth metal ions

“…A c c e p t e d M a n u s c r i p t 3 Some peptides are composed of cyclic units with flat conformation in which all the amino acid side chains pointing outwards while carbonyl and amino groups of the amide backbone are oriented perpendicular to the ring. Selfassembling of these units make the nanotube structure [17].…”

“…Todays, cyclic peptides are of interest because of their applications in biology, chemistry and material sciences [2][3][4][5]. Different fields of application are such as biosensors, photosensitive materials, antimicrobial agents, selective transporter systems, molecular electronics components and other potential uses in biology, electronics and optics [6][7][8][9][10][11][12][13][14][15].…”