Eur. J. Chem. volume 4, issue 3, P195-202 2013 DOI: 10.5155/eurjchem.4.3.195-202.777
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Nadia Ali Ahmed Elkanzi, Hisham Abdallah Abd El-Monem Yosef, Nesrin Mahmoud Morsy Mohamed
Abstract:

KEYWORDSSelective oxidation of 4-amino-2-methyl-5,10-dioxo-1,5,10,10a-tetrahydrobenzo[g]-quinoline-3-carbonitrile (1) with selenium dioxide provided, 4-amino-2-formyl-5,10-dioxo-1,5,10,10a-tetrahydrobenzo[g]quinoline-3-carbonitrile (2). The one-pot reaction of compound 2 with ethyl cyanoacetate and thiourea in ethanol yielded 4-amino-2-(5-cyano-6-oxo-2-thioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-5,10-dioxo-1,5,10,10a-tetrahydrobenzo[g]-quinoline-3-carbonitrile (3). The cycloaddition reaction of chloroacetic …

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