Synthesis of magnetic and fluorescent multifunctional hollow silica nanocomposites for live cell imaging

Preparation and identification of multifunctional mesoporous silica nanoparticles for in vitro and in vivo dual-mode imaging, theranostics, and targeted tracking

“…Furthermore, HeLa cells clearly ingested considerably more EuGd-FA-MSNs than L929 cells. All of these results can be attributed to the overexpression of folate receptors on the membrane surface of HeLa cells [41]. These results also confirm the significantly lower folate receptor expression levels in the normal L929 cell line.…”

Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery

“…MRI has been widely used in clinics for its high spatial resolution and capacity to obtain physiological and anatomical information simultaneously, while more and more attention has been paid to FI due to its high sensitivity and rapid screening capacity. Integration of these two imaging modalities into one mesoporous silica nanoparticle as a dual‐modality contrast agent could be used in a single clinical procedure for pre‐ and post‐operative MRI and intraoperative FI, providing enhanced imaging before, during, and after the procedures ( Figure ) 251, 256, 257. Integrated theranostics by integrating multiple imaging agents into one single mesoporous silica nanoparticle with concurrent drug delivery can monitor the treatment process in real‐time, detect the biodistribution of nanoparticles, and confirm the foci area and margin, which offer great promise for personalized therapy 13, 68, 258–260.…”

Luminescent and magnetic properties of YVO4:Ln3+@Fe3O4 (Ln3+=Eu3+ or Dy3+) nanocomposites

“…Due to their good optical properties, rare-earth (RE) doped yttrium vanadate (YVO 4 ) as luminescent materials has been widely studied [7][8][9][10]. Investigations show that nanosized YVO 4 :Ln 3+ phosphors have a significant application in a high definition flat display panel and potential applications in biology [11][12][13]. Consequently, some groups have been devoted to the investigation of the photoluminescence of YVO 4 :Ln 3+ [14][15][16].…”