Synthesis of Gold Nanoparticles Using Leaf Extract of Ziziphus zizyphus and their Antimicrobial Activity

Abstract

(1) Background: There is a growing need for the development of new methods for the synthesis of nanoparticles. The interest in such particles has raised concerns about the environmental safety of their production methods; (2) Objectives: The current methods of nanoparticle production are often expensive and employ chemicals that are potentially harmful to the environment, which calls for the development of “greener” protocols. Herein we describe the synthesis of gold nanoparticles (AuNPs) using plant extracts, which offers an alternative, efficient, inexpensive, and environmentally friendly method to produce well-defined geometries of nanoparticles; (3) Methods: The phytochemicals present in the aqueous leaf extract acted as an effective reducing agent. The generated AuNPs were characterized by Transmission electron microscopy (TEM), Scanning electron microscope (SEM), and Atomic Force microscopy (AFM), X-ray diffraction (XRD), UV-visible spectroscopy, energy dispersive X-ray (EDX), and thermogravimetric analyses (TGA); (4) Results and Conclusions: The prepared nanoparticles were found to be biocompatible and exhibited no antimicrobial or antifungal effect, deeming the particles safe for various applications in nanomedicine. TGA analysis revealed that biomolecules, which were present in the plant extract, capped the nanoparticles and acted as stabilizing agents.

Gold nano particles synthesized from Strychni semen and its anticancer activity in cholangiocarcinoma cell (KMCH-1)

“…This result matches with the prior studies in which UV-Vis spectroscopy tattered to examine the shape and size of the constrained nanomaterials in the aqueous suspensions [25]. This connected data were previously reputable by a number of investigations on a combination of gold nanoparticles [26]. When compared with the other metal nanoparticles, mainly AuNPs, enfold free electrons which are positioned in SPR (surface plasma resonance) absorption bands due to the united trembling of electrons of metal nanoparticles in consequence with lightwave [27].…”

Synthesis of gold nanoparticles from leaf Panax notoginseng and its anticancer activity in pancreatic cancer PANC-1 cell lines

“…The ocular sign of the colour replacement and the formation of ruby-red colour indicated the formation of the AuNPs; that directs the formation of gold nanoparticles (Figure 1). This related data were previously proved by numerous researches on synthesis of gold nanoparticles [31].…”

Nanoparticle–Plant Interactions: Two‐Way Traffic

“…This technique may prove to be highly effective, quick, economical, and ecofriendly and free of hazardous byproducts. Researchers have used different preparations of plant extracts such as whole plant biomass, aerial parts, leaves, and seeds . These plant parts were macerated in different solvents, including ethanol, distilled water, or deionized water, followed by filtration through a filter paper to separate plant tissue and other debris.…”