Synthesis of copper (II)-supported magnetic nanoparticle and study of its catalytic activity for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones

New Trend for Acceleration Solid Phase Extraction Process Based on Using Magnetic Nano-adsorbents along with Surface Functionalization through Microwave Assisted Solvent-free Technique

“…12,13 The aim of this work is to speed up the overall SPE process for Cu(II) uptake by making the most of both the advantages of fast kinetics of MNPs and short reaction time characteristic for microwave heating for synthesizing silica coating MNPs and aliphatic diamines functionalized adsorbents. Comparing the results with the same adsorbents synthesized via conventional heating 14,15 as a function of Cu(II) uptake capacities and time of equilibration is also planned to measure the success of the new trend. In fact, diamine functionalized adsorbents are widely used for further reactions with organic reagents to maximize selectivity properties and applications as well.…”

Sulfuric acid heterogenized on magnetic Fe3O4 nanoparticles: A new and efficient magnetically reusable catalyst for condensation reactions

“…[14] Besides, 2, 3-dihydroquinazoline-4(1H)-one derivatives can act as key structural motifs to design the new category of highly valuable synthetic drug candidates owing to their important pharmacological properties. [15,16] Recent literature studies clearly shown that a variety of molecules containing 2, 3-dihydroquinazoline-4(1H)-one structural units exhibit a series of significant biological activities such as antitumor, anticancer, antibiotic, antibacterial, antidefibrillatory, antipyretic, and anticonvulsant [17][18][19] The condensation of aryl, alkyl and hetroaryl aldehydes or ketones with anthranil amide in the presence of acidic catalysts is a well-known approach for the synthesis of 2, 3-dihydroquinazoline-4(1H)-ones. [20] In recent times, a variety of catalysts and promoter or reagents for the synthesis of these compounds have been reported in the literature.…”

Magnetic Fe3O4 nanoparticles supported imine/Thiophene‐nickel (II) complex: A new and highly active heterogeneous catalyst for the synthesis of polyhydroquinolines and 2, 3‐dihydroquinazoline‐4(1H)‐ones

“…[17][18][19][20][21] 2, 3-dihydroquinazoline-4(1H)-one and polyhydroquinoline structural motifs have been known to possess diverse biological activities such as antitumor, anticancer, antibiotic, antidiabetic, antibacterial, antidefibrillatory, antipyretic, and anticonvulsant agents. [22][23][24][25][26][27][28][29][30] Polyhydroquinolines also are well-known drugs for the treatment of cardiovascular and Alzheimer's diseases. [31,32] Furthermore, polyhydroquinoline derivatives are well-known as Ca 2+ channel blockers and drugs of NADH co-enzymes.…”