Synthesis of Biginelli adducts using a Preyssler heteropolyacid in silica matrix from biomass building block

Kinetics for the biodiesel production from lauric acid over Keggin heteropolyacid loaded in silica framework

“…In the last decades, heteropolyacids (HPAs) J o u r n a l P r e -p r o o f have emerged as sustainable catalysts in Organic Chemistry due to these have been recognized as economically and environmentally benign acid catalysts due to their acidity and redox propertier for various reactions [18]. We have developed new materials based in them, for the use in the synthesis of heterocycles, eco-compatible oxidations with hydrogen peroxide, and recently in the valorization of biomass derivatives [19][20][21][22].…”

Efficient Synthesis of Novel Biginelli and Hantzsch Products Sourced from Biorenewable Furfurals Using Gluconic Acid Aqueous Solution as the Green Organocatalyst

“…Numerous homogeneous and heterogeneous acid catalysts have been screened for Biginelli and Hantzsch transformations. , Metal-free organocatalysts have shown promising activities for these transformations. , A SciFinder search on the Biginelli product of MF 1b as a model 5-substituted-2-furaldehyde revealed that heterogeneous catalysts, such as sulfated zirconia, Zn 2+ -modified MCM-41, silica-supported sulfonic acid, preyssler heteropolyacids, and titanium silicate had been used that afforded acceptable yields of 4b under moderate reaction conditions. − However, there is still an active search for an efficient, inexpensive, and eco-friendly catalyst that allows the reactions to happen under mild conditions and affords products with desired selectivity and yield . Gluconic acid aqueous solution (GAAS) has received much interest as an acid–based organocatalyst and a green reaction medium for various organic transformations. , Gluconic acid has roughly 10 times stronger Brønsted acidity (p K a = 3.86) than acetic acid (p K a = 4.76) and is nontoxic, nonvolatile, noncorrosive, and biodegradable.…”

Synthesis of novel Biginelli and Hantzsch products from biorenewable furfurals using 1,4‐diazabicyclo[2.2.2]octanium diacetate as a Brønsted acidic ionic liquid catalyst

“…[26][27][28][29] FUR 1 a is typically used to demonstrate the substrate scope of the synthetic processes for DHPMs and DHPs. [30,31] Recently, 5-methylfurfural (MF, 1 b) and HMF 1 e have been used as renewable substrates in the Biginelli reaction for synthesizing novel DHPMs. [30,32] Table 1 presents the literature processes for converting MF 1 b as a model 5-substituted-2-furaldehyde into the corresponding DHPM by Biginelli reaction.…”